Category: <span>Alzheimer’s</span>

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Cleaning up toxic ‘protein clumps’ could prevent dementia
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Cleaning up toxic ‘protein clumps’ could prevent dementia

by University of Queensland Credit: Queensland Brain Institute The clean-up of cellular “protein clumps” could prevent the onset of some types of dementia, according to a new study from The University of Queensland. Researchers from the Queensland Brain Institute made the discovery after focusing on the relationship between the enzyme Fyn and the protein Tau...

Scientists develop new mathematical model of Alzheimer’s disease
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Scientists develop new mathematical model of Alzheimer’s disease

by University of York Diagram of the brain of a person with Alzheimer’s Disease. Credit: Wikipedia/public domain. Scientists have used a mathematical model to reveal how toxic proteins cluster together inside the brain during the early stages of Alzheimer’s. The researchers, from the University of York’s School of Physics, Engineering and Technology, say the discovery...

Study identifies blood pressure drug as potential treatment for Black patients with Alzheimer’s disease
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Study identifies blood pressure drug as potential treatment for Black patients with Alzheimer’s disease

by Cleveland Clinic Cleveland Clinic-led study identifies blood pressure drug as potential treatment for Black patients with Alzheimer’s disease. Credit: Cleveland Clinic Considering how patients from different ethnic groups respond to the same drug could be crucial to finding new Alzheimer’s disease treatments—a disorder the Alzheimer’s Association previously deemed a “silent epidemic” among Black adults....

Green tea and resveratrol reduce Alzheimer’s plaques in lab tests
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Green tea and resveratrol reduce Alzheimer’s plaques in lab tests

by Taylor McNeil, Tufts University “In the case of these compounds that passed the screening, they had virtually no plaques visible after about a week,” says Dana Cairns. This image shows effects of resveratrol compared to control. Credit: Dana Cairns Alzheimer’s disease is the sixth leading cause of death in the United States, affecting more...

A telltale protein spreads throughout the brain in distinct patterns based on patients’ Alzheimer’s phenotype
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A telltale protein spreads throughout the brain in distinct patterns based on patients’ Alzheimer’s phenotype

by Delthia Ricks, Medical Xpress Identification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al., Science Translational Medicine (2022) New imaging of patients with Alzheimer’s demonstrates how a telltale protein spreads throughout the brain based on the phenotype of the disease, i.e., whether the condition is dominated by forgetfulness, or...

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New study expands range of potential Alzheimer’s drugs

UNIVERSITÉ LAVAL Québec City, October 25, 2022 – Alzheimer’s disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease’s hallmarks. That’s according to a study published today in scientific journal Brain by a team from Université Laval and Rush...

Old diabetes drugs slash the risk of dementia by more than a FIFTH, study finds
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Old diabetes drugs slash the risk of dementia by more than a FIFTH, study finds

By MANSUR SHAHEEN DEPUTY HEALTH EDITOR FOR DAILYMAIL.COM PUBLISHED: 18:30 EDT, 11 October 2022 | UPDATED: 18:30 EDT, 11 October 2022 A class of diabetes drugs that have fallen out of fashion may help prevent Alzheimer’s, a major study suggests.  Thiazolidinediones (TZDs) reduced the risk of developing the disease by more than a fifth in a study of more than half...

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Newly identified mechanism may explain why women are more vulnerable to Alzheimer’s disease

Reviewed by Emily Henderson, B.Sc. Oct 4 2022 Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer’s disease-;a finding that they say could help lead to new medicines to treat the disease. Specifically, the researchers found that the female brain shows higher...

Study: Decreased proteins, not amyloid plaques, are tied to Alzheimer’s disease
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Study: Decreased proteins, not amyloid plaques, are tied to Alzheimer’s disease

by University of Cincinnati PET scan of a human brain with Alzheimer’s disease. Credit: public domain New research from the University of Cincinnati bolsters a hypothesis that Alzheimer’s disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question. UC researchers led...

New trial finds first-ever Alzheimer’s drug to slow cognitive decline
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New trial finds first-ever Alzheimer’s drug to slow cognitive decline

By Rich Haridy September 28, 2022 Over 18 months those on lecanemab showed a 27% slower rate of cognitive decline compared to those in the placebo group Depositphotos Pharmaceutical companies Eisai and Biogen have announced the first results from a Phase 3 human trial testing a drug designed to treat symptoms of dementia associated with...