(HealthDay)—Subjects with Alzheimer’s disease have increased levels of two strains of human herpesvirus, according to a study published online July 11 in Neuron. Ben Readhead, M.B.B.S., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues constructed multiscale networks of the late-onset Alzheimer’s disease-associated virome, integrating genomic, transcriptomic, proteomic, and histopathological...
Category: <span>Alzheimer’s</span>
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Newly characterized molecule offers possibilities for novel Alzheimer’s treatments
Alzheimer’s disease is an increasingly prevalent, neurodegenerative condition that erodes memory and other cognitive functions. Treatments for this complex disease have been elusive, although researchers have previously uncovered its main biological features: amyloid-beta plaques and tau tangles. PET scan of a human brain with Alzheimer’s disease. Credit: public domain A study by researchers from Brigham and Women’s Hospital (BWH),...
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First practice guidelines for clinical evaluation of Alzheimer’s disease
July 22, 2018, Alzheimer’s Association Despite more than two decades of advances in diagnostic criteria and technology, symptoms of Alzheimer’s disease and Related Dementias (ADRD) too often go unrecognized or are misattributed, causing delays in appropriate diagnoses and care that are both harmful and costly. Contributing to the variability and inefficiency is the lack of...
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The ‘Big Bang’ of Alzheimer’s: Scientists ID genesis of disease
DALLAS – July 10, 2018 – Scientists have discovered a “Big Bang” of Alzheimer’s disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain. A study from UT Southwestern’s O’Donnell Brain Institute provides novel insight into the shape-shifting nature of a tau molecule...
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Alzheimer’s breakthrough: Brain metals that may drive disease progression revealed
In brains affected by Alzheimer’s, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide UNIVERSITY OF WARWICK Breakthrough in description of metals in brain which may drive the progression of Alzheimer’s disease, made by international research collaboration, including University of Warwick In brains affected by Alzheimer’s, researchers identify chemically reduced iron species, with mineral forms...
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New study suggests viral connection to Alzheimer’s disease
ARIZONA STATE UNIVERSITY Of the major illnesses facing humanity, Alzheimer’s disease (AD) remains among the most pitiless and confounding. Over a century after its discovery, no effective prevention or treatment exists for this progressive deterioration of brain tissue, memory and identity. With more people living to older ages, there is a growing need to clarify...
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Physicists link specific iron forms to Alzheimer’s
There have been indications for decades that there is a link between increased iron levels in the brain and Alzheimer’s disease. Leiden physicists now report a distinction between different forms of iron, identifying specific iron forms that increase in Alzheimer’s patients. The research is published in Scientific Reports. Iron plays an important role in biological processes, including those...
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Music activates regions of the brain spared by Alzheimer’s disease
Ever get chills listening to a particularly moving piece of music? You can thank the salience network of the brain for that emotional joint. Surprisingly, this region also remains an island of remembrance that is spared from the ravages of Alzheimer’s disease. Diagram of brain networks involved in processing attention. Researchers at the University of Utah...
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Alzheimer’s Disease Gene Successfully Removed From Human Brain: Is This The Cure We’ve Been Waiting For?
Scientists were able to successfully remove a gene that caused Alzheimer’s disease from the human brain, possibly paving the way for a new kind of treatment against the dreaded illness. Scientists were able to successfully remove apoE4, a gene that caused Alzheimer’s disease, from the human brain. The research might be science’s best shot at...
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Scientists neutralize and reverse a key genetic risk factor for Alzheimer’s
Alzheimer’s disease has a range of risk factors, but one of the clearest connections is the gene apoE4. Now, researchers at the Gladstone Institutes have peered closer at the protein encoded by this gene and uncovered how it affects the brain, how it increases the risks of Alzheimer’s and most importantly, how the damage can be reversed....