Category: <span>Anti-aging</span>

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AI-powered board game can help reduce social isolation in older adults
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AI-powered board game can help reduce social isolation in older adults

by Catherine Graham, Johns Hopkins University The team visited a local retirement community to test a prototype of their game. Credit: Johns Hopkins University It’s no mystery why online games became an even-more popular pastime during the COVID-19 pandemic: They provide entertainment and social connection, while also keeping our brains stimulated. A new AI-powered game...

Surgery no better for wrist fracture in older adults
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Surgery no better for wrist fracture in older adults

For persons aged 60 years or older with displaced distal radius fracture, surgical treatment seems not to be better than nonsurgical treatment for patient-reported wrist function, according to a study published online April 27 in JAMA Surgery. Andrew Lawson, M.P.H., from the Ingham Institute for Applied Medical Research in Sydney, and colleagues conducted a secondary analysis...

Study suggests obesity paradox for those over 80 due to non-cardiovascular disease mortality
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Study suggests obesity paradox for those over 80 due to non-cardiovascular disease mortality

by Bob Yirka, Medical Xpress Credit: Unsplash/CC0 Public Domain A team of researchers affiliated with multiple institutions in China and the U.S. has found that the obesity paradox for those over 80 is driven mostly by non-cardiovascular disease mortality rates. In their paper published in the journal Nature Aging, the group describes their study of...

Multiple treatments to slow age-related muscle wasting
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Multiple treatments to slow age-related muscle wasting

by University of Basel Skeletal muscle tissue. Credit: University of Michigan Medical School Everyone wants to stay fit and healthy as they grow old. But as we age, our body degrades, our muscles shrink and strength declines. Some older people suffer from excessive muscle loss, a condition known as sarcopenia. University of Basel researchers show...

New approach enhances muscle recovery in aged mice
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New approach enhances muscle recovery in aged mice

UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, NEWS BUREAU IMAGE: UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN KINESIOLOGY AND COMMUNITY HEALTH PROFESSOR MARNI BOPPART, LEFT, CHEMISTRY PROFESSOR JONATHAN SWEEDLER AND THEIR COLLEAGUES DEVELOPED A NEW METHOD TO RECOVER SKELETAL MUSCLE AFTER DISUSE. THEY REPORT THEIR FINDINGS IN THE JOURNAL OF PHYSIOLOGY. CREDIT: PHOTO BY MICHELLE HASSEL CHAMPAIGN, Ill. — Scientists...

Rejuvenation of woman’s skin could tackle diseases of aging
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Rejuvenation of woman’s skin could tackle diseases of aging

By Pallab GhoshScience correspondent IMAGE SOURCE, FÁTIMA SANTOS Image caption, This magnified skin cell is from a 53-year old woman but it looks and behaves like one that is 30 years younger Researchers have rejuvenated a 53-year-old woman’s skin cells so they are the equivalent of a 23-year-old’s. The scientists in Cambridge believe that they...

Chemical compound promotes healthy aging
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Chemical compound promotes healthy aging

by Pennington Biomedical Research Center  Mitochondrial uncoupling makes mitochondria, the power plants of the cell, less efficient. As a result, the mitochondria burn more energy. Elderly mice given BAM15 lost fat, gained muscle and strength, and increased physical activity. Credit: Pennington Biomedical Research Center A recently discovered chemical compound helped elderly mice with obesity lose fat...

Apolipoprotein E destabilizes heterochromatin and drives senescence
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Apolipoprotein E destabilizes heterochromatin and drives senescence

by Zhang Nannan, Chinese Academy of Sciences Nuclear-localized APOE promotes human stem cell senescence. Credit: Liu Guanghui’s lab Prof. Liu Guanghui and his colleagues from the Institute of Zoology and the Beijing Institute of Genomics of the Chinese Academy of Sciences have collaborated to find that Apolipoprotein E (APOE) destabilizes heterochromatin and drives senescence in...

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Effects of Geroprotective Drugs on Skeletal Health are Largely Unknown

The various geroprotective drugs capable of upregulating cellular maintenance processes in order to modestly slowing aging in short-lived laboratory species are a mixed bunch, ranging from the only technically geroprotective, including well characterized, and well used drugs such as aspirin, to drugs with very mixed data for small effects, such as metformin, through to the better end of the...

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Senolytic Treatment Increases Circulating α-Klotho in Mice and Humans

Senescent cells accumulate with age. They are never a very sizable proportion of all cells in a tissue, but they causes a great deal of harm via their inflammatory signaling, changing the behavior of surrounding cells for the worse, and contributing to chronic inflammation throughout the body. All of the common age-related diseases appear to be driven by...