A new study has found that mechanical damage to the cell membrane may induce cellular senescence in human cells.Peer-Reviewed Publication OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY (OIST) GRADUATE UNIVERSITY KINTSUGI, THE TRADITIONAL JAPANESE ART OF REPAIRING BROKEN POTTERY BY MENDING CRACKS WITH LACQUER AND GOLD. KINTSUGI VISIBLY INCORPORATES THE HISTORY OF AN OBJECT INTO ITS...
Category: <span>Anti-aging</span>
J-shaped curve apparent between dietary thiamine and worsening mental acuity
by British Medical Journal Credit: Pixabay/CC0 Public DomainThere seems to be a J-shaped curve between dietary thiamine (vitamin B1) and worsening mental acuity among cognitively healthy older people, suggests research published in the open-access journal General Psychiatry. The sweet spot seems to be a daily intake of 0.68 mg, below which there is relatively little impact....
Age-related changes in fibroblast cells promote pancreatic cancer growth and spread
by Johns Hopkins University School of Medicine Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainOlder people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns...
Study shows salt substitutes help to maintain healthy blood pressure in older adults
by American College of Cardiology Credit: CC0 Public DomainThe replacement of regular salt with a salt substitute can reduce incidences of hypertension, or high blood pressure, in older adults without increasing their risk of low blood pressure episodes, according to a recent study in the Journal of the American College of Cardiology. People who used a...
CAR T cells show promise against age-related diseases in mice
Peer-Reviewed Publication MEMORIAL SLOAN KETTERING CANCER CENTER AN IMMUNOFLUORESCENCE IMAGE OF AN AGED MOUSE LIVER. EXPRESSION OF Β-GALACTOSIDASE (WHITE) AND UPAR (YELLOW) IN SENESCENT CELLS SERVE AS TARGET FOR ENGINEERED CAR T CELLS. ELIMINATION OF THESE CELLS IMPROVED AGE-RELATED METABOLIC DYSFUNCTION. CREDIT: MEMORIAL SLOAN KETTERING CANCER CENTER HighlightsLaboratory research led by MSK and Cold Spring...
Study finds novel macrolide–DEL-1 axis drives bone regeneration in aging individuals
by Niigata University Aging is associated with increased susceptibility to periodontitis due to the reduced expression of DEL-1. Credit: Niigata UniversityResearchers from Niigata University and a University of Pennsylvania team have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to the development of therapeutic agents to...
T cells can be reprogrammed to fight aging
Cold Spring Harbor LaboratoryThe fountain of youth has eluded explorers for ages. It turns out the magic anti-aging elixir might have been inside us all along. Cold Spring Harbor Laboratory (CSHL) Assistant Professor Corina Amor Vegas and colleagues have discovered that T cells can be reprogrammed to fight aging, so to speak. Given the right...
Third major study finds that multivitamin supplements improve memory and slow cognitive aging in older adults
by Mass General Brigham Unsplash/CC0 Public DomainBy 2060, according to the Alzheimer’s Association, nearly one in four Americans will be in an age bracket at elevated risk of cognitive decline and Alzheimer’s disease unless interventions can help preserve cognitive function before deficits begin. The COcoa Supplement and Multivitamin Outcomes Study (COSMOS) is a large-scale, nationwide, randomized...
Loss of cells in pancreas in the elderly may cause age-related diabetes
by Tokyo Metropolitan University Two different ways in which islet cell loss can be observed (top left and right) . The relationship between the percentage of pancreatic beta cells and islet cell loss (bottom left). The number of mild and severe cases of ICL at different ages (bottom right). Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metropolitan...
New analysis reveals how skin microbiome could be associated with wrinkles and skin health
by Cassidy Symons, University of California – San Diego Credit: Unsplash/CC0 Public DomainThe effects of aging and external factors like UV exposure on skin are well documented. As people age or spend more time in the sun, their skin tends to become drier and more wrinkled, Recent findings have identified an exciting potential new link to...