by Niigata University Aging is associated with increased susceptibility to periodontitis due to the reduced expression of DEL-1. Credit: Niigata UniversityResearchers from Niigata University and a University of Pennsylvania team have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to the development of therapeutic agents to...
Cold Spring Harbor LaboratoryThe fountain of youth has eluded explorers for ages. It turns out the magic anti-aging elixir might have been inside us all along. Cold Spring Harbor Laboratory (CSHL) Assistant Professor Corina Amor Vegas and colleagues have discovered that T cells can be reprogrammed to fight aging, so to speak. Given the right...
by Mass General Brigham Unsplash/CC0 Public DomainBy 2060, according to the Alzheimer’s Association, nearly one in four Americans will be in an age bracket at elevated risk of cognitive decline and Alzheimer’s disease unless interventions can help preserve cognitive function before deficits begin. The COcoa Supplement and Multivitamin Outcomes Study (COSMOS) is a large-scale, nationwide, randomized...
by Tokyo Metropolitan University Two different ways in which islet cell loss can be observed (top left and right) . The relationship between the percentage of pancreatic beta cells and islet cell loss (bottom left). The number of mild and severe cases of ICL at different ages (bottom right). Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metropolitan...
by Cassidy Symons, University of California – San Diego Credit: Unsplash/CC0 Public DomainThe effects of aging and external factors like UV exposure on skin are well documented. As people age or spend more time in the sun, their skin tends to become drier and more wrinkled, Recent findings have identified an exciting potential new link to...
Bioelectrical impedance analysis enables quick and easy monitoring of muscular health, addressing the impact of aging and conditions such as sarcopeniaPeer-Reviewed Publication SHIBAURA INSTITUTE OF TECHNOLOGY AS INDIVIDUALS AGE, THEY ARE MORE AT RISK OF LOSING MUSCLE. BY PROVIDING THEM WITH A MEANS TO QUICKLY ASSESS MUSCULAR HEALTH WITH PHASE ANGLE MEASUREMENTS, INDIVIDUALS CAN TAKE...
Peer-Reviewed Publication MASS GENERAL BRIGHAM Myosteatosis, or aging-related fat accumulation in skeletal muscles, is a leading cause of declines in muscle strength and quality of life in elderly adults. Older adults who are sedentary and develop accumulated fat in the skeletal muscle are often prescribed exercise by their doctors to combat the condition. If scientists...
by University of Michigan Credit: Pixabay/CC0 Public Domain A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence. In 1957, evolutionary biologist George Williams proposed that genetic mutations that contribute to aging...
by Elsevier Resolvin-D2 (RvD2), when added ex vivo, acted directly on the bone marrow to induce a specific increase in monocyte/macrophage progenitors and reduce steatosis and collagen deposition. Credit: The American Journal of Pathology Aging is associated with chronic, nonresolving inflammation, or “inflammaging,” that can lead to tissue dysfunction. New findings reported in The American Journal...
Researchers from Osaka University have shown for the first time that damaged lysosomes are repaired by a process called microautophagy, which is essential for preventing aging Peer-Reviewed Publication OSAKA UNIVERSITY OVERVIEW: LYSOSOMES ARE REPAIRED BY ESCRT-DRIVEN MICROAUTOPHAGY, AND STK38 AND GABARAPS ARE KEY REGULATORS OF THIS PROCESS BY RECRUITING ESCRTS TO LYSOSOMES. THESE REGULATORS ARE...
