Category: <span>Anti-aging</span>

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Dried goji berries may provide protection against age-related vision loss

UNIVERSITY OF CALIFORNIA – DAVIS Regularly eating a small serving of dried goji berries may help prevent or delay the development of age-related macular degeneration, or AMD, in healthy middle-aged people, according to a small, randomized trial conducted at the University of California, Davis. AMD is the leading cause of vision loss in older people, and is estimated...

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Green-Med Diet Seems to Slow Age-Related Neurodegeneration

BEN-GURION UNIVERSITY OF THE NEGEV BEER-SHEVA, Israel, January 13, 2022 – A green Mediterranean diet, high in polyphenols and low in red and processed meat, seems to slow age-related brain atrophy, according to a new Ben-Gurion University of the Negev-led international study. The DIRECT PLUS 18-month long randomized control trial among ~300 participants is one...

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Self-perceptions of aging and stress have significant impact on physical health, study finds

by Molly Rosbach, Oregon State University Credit: CC0 Public Domain As adults age, it’s common to start thinking about how getting older affects their energy, physical health, and cognitive well-being. But dwelling on negative aspects of aging can have a measurable negative impact on your physical health and ability to respond to stress, a recent study from Oregon...

Astrocytes and Microglia Both Help and Harm the Blood-Brain Barrier in Aging
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Astrocytes and Microglia Both Help and Harm the Blood-Brain Barrier in Aging

The blood-brain barrier wraps blood vessels where they pass through the central nervous system, controlling the passage of cells and molecules into and out of the brain. The blood-brain barrier becomes disrupted with age, allowing unwanted molecules into the brain, where they can spur chronic inflammation and dysfunction contributing to neurodegeneration. Researchers here investigate the response of astrocytes and microglia, supporting...

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The Aging Kidney Harms the Brain

A good deal of evidence points to declining kidney function as a cause of declining cognitive function in aging. There are strong correlations between loss of kidney function and risk of dementia, for example. Correlation isn’t a smoking gun in matters of aging, however: it is possible for any one of the underlying forms of molecular damage that cause aging, or...

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What is the Contribution of Demyelination to Cognitive Decline in Aging?

Myelin is an insulator that sheaths the axons forming nervous system connections. It is essential to the correct electrochemical function of the nervous system. Severe conditions such as multiple sclerosis result when myelin is lost, degrading nervous system function to the point of disability and death. In normal aging, myelin is also lost, though to...

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Sirtuins Remain an Active Area of Research in Aging

Sirtuins are connected to the upregulation of cellular stress response mechanisms triggered by, for example, calorie restriction. Given the failure of past attempts to intervene in aging at the point of sirtuin 1, it may be that the influence of sirtuins on the pace of aging simply isn’t large enough to be useful. That said, work on other sirtuins, such as...

Keeping the aging brain connected with words and music
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Keeping the aging brain connected with words and music

by Vibhav Nandagiri, Duke Research Blog  Relative location of subcortical white matter fiber tracts (lateral view). Credit: Wikipedia In an era of seemingly endless panaceas for age-based mental decline, navigating through the clutter can be a considerable challenge. However, a team of Duke researchers, led by cognitive neuroscientist Edna Andrews, Ph.D., think they may have found...

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Senolytic Treatment Improves Muscle Regeneration in Old Mice Only

Senescent cells accumulate with age. Researchers here provide evidence for yet another age-related decline to be added to the long list of issues in which this accumulation of senescent cells is an important contributing cause. In this case, the problem is the loss of regenerative capacity in muscle tissue that occurs with age. Can this...