by Johns Hopkins University Bloomberg School of Public Health Older adults with depression may be at much higher risk of remaining depressed if they are experiencing persistent or worsening sleep problems, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health. The researchers, who published their findings online April 30 in...
By Nick Lavars Central to a lot of scientific research into aging are tiny caps on the ends of our chromosomes called telomeres. These protective sequences of DNA grow a little shorter each time a cell divides, but by intervening in this process, researchers hope to one day regulate the process of aging and the...
by Fritz Lipmann Institute on the proteome of the intestinal epithelium and leads to age-related impairments in adaptation to nutrient availability. (Source: FLI / Alessandro Ori & Nadja Gebert. Created with BioRender.com) The small intestine is one of the most important interfaces between the environment and our body. It is responsible for nutrient absorption but...
In this open access paper, researchers present evidence to suggest that the mitochondrial dysfunction that accompanies aging may be a meaningful cause of the loss of neurons that contributes age-related hearing loss, in the sense that it increases the incidence of necroptosis, a form of programmed cell death. Present thinking on the progressive deafness of...
What The Study Did: About 3,800 adults 40 and older in South Korea participating in a national health survey were included in this analysis that examined associations between hearing loss and a test of their ability to retain balance. Age-related hearing loss affects the inner ear, which may increase the risk of dizziness. Authors: Sung-Won...
by Children’s Hospital Boston Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely. Using cells donated by patients with the disease, researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center identified several small molecules that appear to reverse...
The size of the contribution of stochastic nuclear DNA damage to aging is debated. It causes cancer, when rare combinations of cancerous mutations occur and suppression of those early cancerous cells fails, but can it give rise to a meaningful degree of tissue dysfunction otherwise? The present consensus is that most such damage is irrelevant,...
A senescent cell ceases replication and secretes inflammatory and pro-growth signals. The process serves a useful function when such cells are present for a short time and then destroyed, aiding in suppression of cancer and in wound healing. When senescent cells linger, they cause chronic inflammation and significant disruption to tissue function, however. This is...
by Li Yuan, Chinese Academy of Sciences Transcranial ultrasound stimulation (TUS) is emerging as a non-invasive brain stimulation method that can achieve a highly focused stimulation of deeper brain areas. The hypothalamus is the link between the endocrine and nervous systems. Previous studies showed that ultrasound could induce brain activityand the sensory discrimination ability of...
by Okinawa Institute of Science and Technology Globally, human society is aging. A side-effect of this is that age-related disorders, such as frailty, are becoming increasingly common. Frailty includes not only physical disabilities, but also a decline in cognitive function and an increase in various social problems. The prevalence of this disorder among those aged...
