Published on: July 25, 2023 Alex Biese Receiving a diagnosis of breast cancer and radiation treatment were both associated with increased rates of biological aging among patients who participated in a recent study. Women who have received a diagnosis of and treatment for breast cancer tend to age faster than cancer-free women, according to a...
by Josh Barney, University of Virginia Age-related changes in whole-blood gene expression are associated with increased inflammatory gene transcription and decreased expression of genes encoding mitochondrial Ca2+ transport. Credit: Nature Aging (2023). DOI: 10.1038/s43587-023-00436-8 University of Virginia School of Medicine researchers have discovered a key driver of chronic inflammation that accelerates aging, a finding that could lead to longer, healthier...
by Impact Journals LLC Reprogramming small molecule cocktails restore NCC alterations in senescent cells. (A) Chemical structures of small molecules of basal cocktails used to generate induced pluripotent stem cells (iPSCs) from mouse (left) or human (right) somatic cells. (B) Correlation heatmaps showing eGFP and mCherry colocalization in human senescent fibroblasts demonstrate the effects of...
by British Medical Journal Credit: Pixabay/CC0 Public Domain Midlife structural changes to the jawbone may signal subsequent height loss in women, suggests research published in the open access journal BMJ Open. Dentists, who are likely to spot these on mouth X-rays during routine check-ups, should collaborate with patients’ doctors as this may open up opportunities for prevention, suggest the...
Published: July 6, 2023 8.27am EDT Author Ellen QuarlesAssistant Professor in Molecular, Cellular, and Developmental Biology, University of Michigan You likely know someone who seems to age slowly, appearing years younger than their birth date suggests. And you likely have seen the opposite – someone whose body and mind seem much more ravaged by time than...
by Pacific Northwest National Laboratory Scientists have taken an important step forward in predicting who will develop type 1 diabetes months before symptoms appear. In a paper published online on June 29 in Cell Reports Medicine, researchers at the Department of Energy’s Pacific Northwest National Laboratory and their colleagues identify a set of altered proteins that predict...
by Impact Journals LLC Blood methionine level at day 15 (A) and day 29 (B). Credit: 2023 Kubota et al Obesity increases with aging. Methionine restriction affects lipid metabolism and can prevent obesity in mice. In a new study published in the journal Aging, researchers from AntiCancer Inc., University of California San Diego and Showa University School of...
JOHNS HOPKINS MEDICINE In an eight-year study of more than 600 community-dwelling older adults, Johns Hopkins Medicine researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because...
by University of Tsukuba Social mediator robot. Credit: University of Tsukuba Social Mediator Robots (SMRs), which facilitate communication by mediating messages among people, are considered to prevent isolation in elderly individuals. To avoid isolation, it is crucial for the elderly to talk about their daily problems to others (self-disclosure). SMRs that support such self-disclosure are being...
By Dr. Liji Thomas, MD Jun 16 2023 Reviewed by Lily Ramsey, LLM Aging is a physiological function change affecting life at all scales, from cell to organ level. The drivers of this alteration are still largely unknown. However, shifts in the concentration of various molecules occur with aging. In this respect, an interesting new...
