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Similarity between vitamin B12 loss and multiple sclerosis revealed

Findings identify molecular signaling pathway that could enhance current MS treatmentsPeer-Reviewed Publication SANFORD-BURNHAM PREBYS VITAMIN B12 IS ESSENTIAL NUTRIENT THAT SUPPORTS HEALTHY DEVELOPMENT AND FUNCTIONING OF THE CENTRAL NERVOUS SYSTEM. CREDIT: NONE For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and...

A spinal muscle’s size and shape is linked to body fat, according to new Concordia research
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A spinal muscle’s size and shape is linked to body fat, according to new Concordia research

A study of Stingers athletes reveals new connections with body composition parametersPeer-Reviewed Publication CONCORDIA UNIVERSITY MARYSE FORTIN CREDIT: CONCORDIA UNIVERSITY A new study carried out by researchers at Concordia’s School of Health provides a new way of looking at the spine. The research reveals the way one spinal muscle’s size, shape and function relates to...

Study links back pain to a subtype of cells in spinal ‘shock absorbers’
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Study links back pain to a subtype of cells in spinal ‘shock absorbers’

by Cedars-Sinai Medical Center Credit: CC0 Public Domain A new Cedars-Sinai study might have cracked the mystery surrounding the cause of a specific type of back pain. Almost 40% of the adult population experiences low back pain due to degenerating disks in the spine, but medical science hasn’t understood exactly why the disks become painful. In...

Unlocking the secrets of peptide sequences in cells with AI
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Unlocking the secrets of peptide sequences in cells with AI

by University of Waterloo Credit: CC0 Public Domain Machine learning is now helping researchers analyze the makeup of unfamiliar cells, which could lead to more personalized medicine in the treatment of cancer and other serious diseases. Researchers at the University of Waterloo developed GraphNovo, a new program that provides a more accurate understanding of the peptide...

New study sheds light on the link between lipids and cholelithiasis
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New study sheds light on the link between lipids and cholelithiasis

Peer-Reviewed Publication FIRST HOSPITAL OF JILIN UNIVERSITY IMAGE: ASSOCIATIONS OF SERUM LIPIDS WITH CHOLELITHIASIS FROM MENDELIAN RANDOMIZATION. (A) CAUSAL EFFECTS OF GENETICALLY−LOWERED LIPIDS ON CHOLELITHIASIS. (B) RESULTS OF MULTIVARIABLE MENDELIAN RANDOMIZATION ANALYSIS. (C) RESULTS OF NONLINEAR MENDELIAN RANDOMIZATION ANALYSIS.view more CREDIT: BY CHEN L, QIU W, SUN X, ET AL. A new study published in...

Scientists discover key step to kidney fibrosis
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Scientists discover key step to kidney fibrosis

by Bill Snyder, Vanderbilt University EGFR was highly expressed in kidney myofibroblasts from both male and female patients. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43226-xResearchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury...

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Study Looks at RNA’s Solo Act on the Ever-Changing Stage of Cellular Dynamics

RNA has been in the limelight for its starring role in cutting-edge vaccine technology, but RNA molecules are also key players in the inner workings of cells. Researchers have found that RNA molecules can undergo phase separation in a temperature-dependent manner, and this phase behavior is supported by magnesium ions in solution. Here, CAG-repeat RNA...

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Lipid Nanoparticles That Deliver mRNA to T Cells Hold Promise for Autoimmune Diseases

Autoimmune disorders are among the most prevalent chronic diseases across the globe, affecting approximately 5-7% of the world’s population. Emerging treatments for autoimmune disorders focus on “adoptive cell therapies,” or those using cells from a patient’s own body to achieve immunosuppression. These therapeutic cells are recognized by the patient’s body as ‘self,’ therefore limiting side...

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How Cell Identity is Preserved when Cells Divide

Posted Today MIT study suggests 3D folding of the genome is key to cells’ ability to store and pass on “memories” of which genes they should express. HeLa cells stained for nuclear DNA with the blue fluorescent Hoechst dye. On the left, a cell is going through mitosis and its DNA has condensed. Every cell in...

Key discovery opens new avenue to lowering cholesterol levels
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Key discovery opens new avenue to lowering cholesterol levels

By Paul McClure Researchers have discovered a previously unknown step in how the body processes dietary cholesterol Depositphotos Researchers have identified a previously unknown step in the process by which dietary cholesterol is absorbed from the intestine into the bloodstream. The newfound pathway provides a potential new target for treating high cholesterol. High cholesterol is a...