Professor Amiram Goldblum and his team at the Hebrew University of Jerusalem’s Institute for Drug Research have discovered 27 new molecules. These molecules all activate a special protein called PPAR-delta and have the potential to treat fatty liver disease, obesity, diabetic nephrotoxicity, and to heal wounds. MAGE: THIS IS PROFESSOR AMIRAM GOLDBLUM.view more CREDIT: HEBREW...
Category: <span>biological sciences</span>
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Tweaking of hormone-producing cells in the intestine
Researchers from the group of Hans Clevers at the Hubrecht Institute (KNAW) in the Netherlands and their collaborators shed new light on the origin and function of hormone producing cells in the intestine and open new avenues to tweak gut hormone production to treat human disease. Their results were recently published in Nature Cell Biology...
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Discovery could improve cystic fibrosis treatment
Researchers exploring the effects of a long-standing treatment for cystic fibrosis have discovered a potential new target for drugs to treat the disease, which has no cure and typically cuts decades off the lives of patients. Cystic fibrosis affects the lungs and other organs, primarily by making the mucus that lines the lungs viscous, clogging...
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New treatment target emerging for retinal damage
Scientists at the Medical College of Georgia at Augusta University are looking at new treatment targets for the retinal damage that often accompanies diseases like diabetes, glaucoma and hypertension. Dr. Abdelrahman Y. Fouda. Credit: Phil Jones, Senior Photographer, Augusta University Characterized by damage to the blood vessels, those diseases often lead to ischemia—or a disruption of...
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Measles outbreak in Washington State
The latest update from the county’s health department said that 23 measles cases have been confirmed and two more suspected cases are under investigation, CBS News reported. Most cases involve children ages 1 to 10 years. Four cases are in youngsters ages 11 to 18, and one case is in a person between ages 19...
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Anatomy of surprise: Scientists discover hidden blood networks that cross through bone
For years, physiologists looking closely at bones noticed something puzzling. It was a microscopic prison break, blood cells slipping unseen from the enclosed depths of the bone marrow into the general circulation. “We have the bone marrow, which produces the blood cells, and when you need them, you need them urgently. But how do they...
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How long do people need to be monitored after fainting?
For the first time, physicians in the Emergency Department (ED) have evidence-based recommendations on how best to catch the life-threatening conditions that make some people faint. New research published in Circulation suggests that low-risk patients can be safely sent home by a physician after spending two hours in the ED, and medium and high-risk patients...
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Study uncovers cause of bone loss in joint implant patients
Rutgers researchers have discovered the long-sought reason that many people with joint replacements experience harmful inflammation and bone loss. A major contributing factor to joint replacement failure is microparticles released from the prosthetic devices — known as “wear debris” — which are thought to promote inflammation, leading to pain, disappearance of bone tissue, loosening of...
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Outbreak of paralyzing disease linked to non-polio enterovirus through TGen-led study
PHOENIX, Ariz. — Jan. 22, 2019 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a polio-like virus as a potential cause of an outbreak of a disease known as Acute Flaccid Myelitis (AFM), a crippling condition that causes muscle weakness and paralysis usually among children. At the request...
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Zinc deficiency may play a role in high blood pressure
Zinc deficiency is common in people with chronic illnesses such as type 2 diabetes and chronic kidney disease. People with low zinc levels are also at a higher risk for hypertension. The way in which the kidneys either excrete sodium into the urine or reabsorb it into the body–specifically through a pathway called the sodium...