By Hidaya Aliouche, B.Sc.Reviewed by Sophia Coveney Supernatants are recovered organelle factions of the cell produced after crystallization, precipitation, centrifugation, or other processes that separate cellular extracts. It is also called the supernate. The supernatant is typically free of precipitate, translucent, and of lower density than the precipitate, which typically settles in its layer or...
AUGUST 8TH, 2023 CONN HASTINGS MEDICINE, PUBLIC HEALTH, UROLOGY Researchers at ETH Zurich have developed a bacteriophage system to identify and treat bacterial bladder infections. Bacteriophages are viruses that infect bacteria, but these microorganisms have fallen out of favor as a treatment method for infection since antibiotics came along. Well, antibiotics are looking increasingly shaky as bacteria...
by Institute for Systems Biology Graphical Abstract. Credit: Cell Reports (2023). DOI: 10.1016/j.celrep.2023.112875 Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), the world’s deadliest infectious disease. Mtb is so successful and harmful because it can adapt to different conditions inside our bodies, allowing it to evade treatment. By using a computer model to understand Mtb’s...
by Science China Press In this study, researchers provided a single-cell transcriptomic landscape of mouse ovarian mesenchymal cells and analyzed the cellular and molecular changes of ovarian stroma cell during reproductive aging. Based on bioinformatics analysis, the team provided an interested anti-reproductive aging strategy by improving the quality of ovarian stroma cells in the aged ovary. Credit: Science...
by Elliott Rouse, The Conversation How much would these robo-boots be worth to you? Credit: Neurobionic Lab/University of Michigan Robotics Department, CC BY-ND My colleagues and I have used a tool from economics to measure the costs and benefits of wearing an exoskeleton, and we found that it offers a modest average benefit of US$3.40 per hour...
Peer-Reviewed Publication AMERICAN CHEMICAL SOCIETY IMAGE: CANDYCOLLECT, PICTURED HERE, COULD REPLACE THROAT SWABS TO DIAGNOSE RESPIRATORY ILLNESSES, INCLUDING STREP THROAT CREDIT: ADAPTED FROM ANALYTICAL CHEMISTRY, 2023, A lollipop might be a sweet reward for a kid who’s endured a trip to the doctor’s office, but now, this candy could make diagnostic testing during a visit...
CGTN Share New research suggests smartwatches can track data that allows AI to find Parkinson’s disease seven years before obvious symptoms appear. /alvarez/Getty Creative/CFP Smartwatches can track data that allows artificial intelligence (AI) programs to find Parkinson’s disease as early as seven years before symptoms show, according to a new study. The landmark report opens...
by New York University Credit: Unsplash/CC0 Public Domain Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology. The study by researchers at New York University, Columbia University, and the New York Genome Center, combines a deep learning model with CRISPR screens to control...
EUROPEAN MOLECULAR BIOLOGY LABORATORY IMAGE: THREE-DIMENSIONAL RENDERING OF THE HEXASOME WITH A CHROMATIN REMODELER BOUND TO A DNA MOLECULE. CREDIT: CREDIT: LUIS HAUPTMANN/EMBL In 1983, scientists discovered hexasomes – a unique molecular structure that helps cells package their DNA. Now, a study conducted by the Eustermann group at EMBL Heidelberg has shed light on how DNA packaging...
WILEY Antitumor agents must kill off cancer cells while protecting healthy tissue and having no toxic side-effects. A novel approach based on “self-immolative” polyferrocenes—copolymers that split apart into their components as soon as they enter a tumor cell—could meet these demands. The drugs they hold then synergistically cause an abrupt increase in free radicals and...
