By Paul McClure Researchers have added an active Rac2 protein to macrophages, causing them to cannibalize other immune cells Depositphotos Following a trail of evidence that started with a study of fruit flies nearly 25 years ago, researchers have found adding a hyperactive form of the protein Rac2 to macrophages, immune cells that eat pathogens, causes...
Category: <span>Cancer</span>
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Can Particles in Dairy and Beef Cause Cancer and MS?
Angela Speth, MD In our Western diet, dairy and beef are ubiquitous: Milk goes with coffee, melted cheese with pizza, and chili with rice. But what if dairy products and beef contained a new kind of pathogen that could infect you as a child and trigger cancer or multiple sclerosis (MS) 40-70 years later? Researchers...
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Scientists use organoid model to identify potential new pancreatic cancer treatment
by Weill Cornell Medical College Perhexiline maleate induces cell death of human pancreatic cancer organoids. (Red: Cell death marker; Blue: DAPI). Credit: Xiaohua DuanA drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell...
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Allogeneic HCT after primary induction failure beneficial in leukemia
by Elana Gotkine For patients with acute myeloid leukemia (AML), immediate allogeneic hematopoietic stem cell transplantation (HCT) after primary induction failure (PIF) offers long-term survival benefit, according to a study published online Dec. 10 in the Blood Cancer Journal. Miriam Mozaffari Jovein, M.D., from the University of Freiburg in Germany, and colleagues retrospectively assessed long-term...
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Molecular jackhammers’ ‘good vibrations’ eradicate cancer cells
Light-induced whole-molecule vibration can rupture melanoma cells’ membrane The Beach Boys’ iconic hit single “Good Vibrations” takes on a whole new layer of meaning thanks to a recent discovery by Rice University scientists and collaborators, who have uncovered a way to destroy cancer cells by using the ability of some molecules to vibrate strongly when...
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Mechanics of Breast Cancer Metastasis Discovered, Offering Target for Treatment
The most lethal feature of any cancer is metastasis, the spread of cancer cells throughout the body. New research, led by Penn State, reveals for the first time the mechanics behind how breast cancer cells may invade healthy tissues. The U.S. National Science Foundation-supported discovery, showing that a motor protein called dynein powers the movement...
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Hard to Drug: Protein Droplets Reveal New Ways to Inhibit Aggressive Form of Prostate Cancer
Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge, especially when treating aggressive forms of prostate cancer. An international team of researchers from the Institute for Research in Biomedicine in Barcelona, the Max Planck Institute...
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New personalized therapy improves survival for patients with CLL leukemia, phase 3 trial finds
by University of Leeds Credit: Pixabay/CC0 Public Domain Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase 3 trial has found. The trial, by the University of Leeds, is published in the New England Journal of Medicine and has been presented at the 65th...
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Landscape for acute myeloid leukemia patients evolving rapidly as research discoveries advance new treatments
by University of Miami Leonard M. Miller School of Medicine Acute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public Domain The treatment landscape for acute myeloid leukemia (AML) is evolving rapidly, as research discoveries at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and other academic cancer centers advance new, more effective therapies...
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Manipulation of gut microbiota with flaxseed could reduce breast cancer risk
Peer-Reviewed Publication AMERICAN SOCIETY FOR MICROBIOLOGY Washington, D.C.— A new study demonstrates that the human gut microbiome may be a factor in breast health. Lifestyle and diet have long been known to affect human health. In the study, flaxseed components called lignans were shown to influence the relationship between gut microorganisms and the expression of...