Front Pharmacol. 2017; 8: 875.Published online 2017 Nov 28. doi: 10.3389/fphar.2017.00875PMCID: PMC5712354PMID: 29234282Effect of Methanolic Extract of Dandelion Roots on Cancer Cell Lines and AMP-Activated Protein Kinase PathwayGauhar Rehman,1 Muhammad Hamayun,2 Amjad Iqbal,3 Sumera Afzal Khan,4 Hamayoon Khan,5 Adeeb Shehzad,6 Abdul Latif Khan,7 Anwar Hussain,2 Ho-Youn Kim,8 Jamshaid Ahmad,4 Ayaz Ahmad,9 Abid Ali,1 and In-Jung...
by The Francis Crick Institute Credit: CC0 Public Domain A group of researchers led by the Francis Crick Institute, working with the National Physical Laboratory (NPL) and Imperial College London, have discovered that breast cancer cells expressing a cancer-driving gene heavily rely on vitamin B5 to grow and survive. The researchers are part of Cancer...
November 01, 2023 by William Weir Using nanoparticles administered directly into the cerebrospinal fluid (CSF), a research team has developed a treatment that may overcome significant challenges in treating a particularly deadly brain cancer. The researchers, led by professors Mark Saltzman, PhD, and Ranjit Bindra, MD, PhD, administered to mice with medulloblastoma a treatment that...
by Duke University Credit: Unsplash/CC0 Public Domain For too long, cancer treatment has been a double-edged sword—the very treatments designed to kill cancer cells often wrought havoc on healthy ones too. But a new study published online Oct. 30 in Immunity unveils an approach to cancer treatment that researchers describe as more precise, long-lasting, and less...
by QIMR Berghofer Integrative analysis of samples from patients with AML. a, Unsupervised hierarchical clustering analysis on the expression of 300 transcripts with the greatest variance-to-mean ratios among 30 individual AMLs from our repository that can successfully generate AML PDX. MLD, multi-lineage dysplasia; MDS, myelodysplastic syndromes; MLL, mixed-lineage leukemia; NOS, not otherwise specified. b, Key...
Peer-Reviewed Publication CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) FROM LEFT TO RIGHT: IVÁN PLAZA-MENACHO, SENIOR AUTHOR, AND FIRST AUTHORS JULIA CONTRERAS AND HIPÓLITO NICOLÁS CUESTA HERNÁNDEZ.view more CREDIT: ESTHER SÁNCHEZ / CNIOIn the late 1970s, the relationship between the c-Src gene and cancer was discovered. The first oncogene was identified.Since then, c-Src has been found...
By Paul McClureOctober 29, 2023Protein discovery could be used to stop breast cancer in its tracks Researchers have discovered a protein that is crucial to enabling the spread of breast cancer to healthy tissues DepositphotosResearchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into...
by Translational Genomics Research Institute SIWA318H treatment depletes p16INK4a positive cells and reduces αSMA expression in PSN1 xenograft tumors. (A) Quantification of the number of p16INK4a positive cells in isotype control antibody treated and SIWA318H treated tumors. (B) Quantification of αSMA positive areas in isotype control antibody treated and SIWA318H treated tumors. (C) A representative image...
Sharon Worcester, MA August 29, 2023 Depression and anxiety were not associated with outcomes for most cancer types, including breast cancer, prostate cancer, and alcohol-related cancer, according to findings from a large, individual participant data meta-analysis. An exception was for lung and smoking-related cancers, but key covariates appeared to explain the relationship between depression, anxiety, and these...
by Society of Nuclear Medicine Representative PET images of 89ZrDFO-trastuzumab displaying %ID/g acquired 48 hours after radiolabeled trastuzumab injection on day 39 for T-DM1 single-treatment regime, T-DM1/statin single-treatment regime, T-DM1 multiple-treatment regime, and T-DM1/statin multiple-treatment regime. Tumor location is indicated by arrow. Credit: Journal of Nuclear Medicine (2023). DOI: 10.2967/jnumed.122.265172A novel therapeutic approach that combines human epidermal...
