Vitamin C–filled foods are the go-to when hoping to help prevent illness or speed up the recovery process. Now this vitamin may help with not only the common cold but cancer as well. Loss of Tet2 protein function, which regulates transcription and plays an important role in blood cell production, underlies some cases of blood...
Category: <span>Cancer</span>
Modulation of anti-tumor immunity by the brain’s reward system
Abstract Regulating immunity is a leading target for cancer therapy. Here, we show that the anti-tumor immune response can be modulated by the brain’s reward system, a key circuitry in emotional processes. Activation of the reward system in tumor-bearing mice (Lewis lung carcinoma (LLC) and B16 melanoma) using chemogenetics (DREADDs), resulted in reduced tumor weight....
Targeting one hormone may help treat bowel cancer
By Catharine Paddock PhD Fact checked by Jasmin Collier Scientists in Spain have discovered a mechanism that promotes inflammation-related bowel cancer and could offer new treatment targets. The finding concerns the activity of the signaling protein p38 in the myeloid cells of the immune system and that of IGF-1, which is a hormone triggered by p38. Researchers...
Yale cancer researchers suggest new treatment for rare inherited cancers
YALE UNIVERSITY New Haven, Conn. — Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their DNA. The discovery, published today in Nature Genetics, suggests a promising strategy for treatment with drugs recently approved for other forms of cancer, said the...
X-rays burst chemo-filled nanobubbles for targeted cancer drug delivery
Researchers at the Center for Nanoscale BioPhotonics (CNBP) have developed a new targeted treatment for cancer. Chemotherapy drugs are wrapped in “nano-bubbles” called liposomes, which are then injected into the desired part of the body and made to release their payload on demand, by applying X-ray radiation. A new potential cancer treatment uses nanobubbles called...
Testosterone research brings new hope for cancer patients
TEXAS A&M UNIVERSITY Many cancer patients suffer from a loss of body mass known as cachexia. Approximately 20 percent of cancer-related deaths are attributed to the syndrome of cachexia, which in cancer patients is often characterized by a rapid or severe loss of fat and skeletal muscle. Dr. Melinda Sheffield-Moore, professor and head of the...
Discovery of a new on/off switch affecting cell-to-cell communications
A new study published in the prestigious journal Molecular Cell INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE – INRS Cellular functions rely on several communications networks that allow cells to rapidly respond to signals affecting the organism. A new study published in the prestigious journal Molecular Cell has revealed a mechanism that shuts down a major cell-to-cell communications...
Glue-like protein may be key to drug-resistant breast cancer
Scientists have found it challenging to understand why some breast cancers become resistant to drugs. A recent study concludes that a sticky protein might be the answer. A glue-like protein may help to explain breast cancer drug resistance. The hormone estrogen plays a vital part in the development of breast cancer. An estimated 70 percent of all breast cancers are...
Study finds mutation driving deadlier brain tumors and potential therapy to stop it
July 9, 2018, Perelman School of Medicine at the University of Pennsylvania A poorly understood mutation in the brain cancer glioblastoma (GBM) is now being implicated for the first time as the driver of rare but deadlier cases of the disease, a team of researchers from the Perelman School of Medicine at the University of Pennsylvania and the...
CAR-T cell therapy and cancer
CAR-T therapy has proven to show good results in a range of patients both young and old. This type of immunotherapy teaches T cells to recognize and destroy cancer much more reliably. In some patients, this leads to the total elimination of cancer. There is also a significant amelioration of the disease in others. What...