by Bob Yirka , Medical Xpress Dietary pro-oxidant therapy using a vitamin K precursor. Credit: Science (2024). DOI: 10.1126/science.adk9167 A team of molecular biologists and other medical specialists at Cold Spring Harbor Laboratory in New York, working with a large number of international partners, reports evidence that a synthetic vitamin K precursor can be used to slow...
Category: <span>Cancer</span>
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New insights show ASCL1’s role in neuroendocrine prostate cancer, an aggressive and treatment-resistant type
by Jim Stallard, Memorial Sloan Kettering Cancer Center Molecular characterization of PtPM and RPM primary prostate tumor transplants demonstrates emergence of neuroendocrine carcinoma marker expression. Credit: Nature Cancer (2024). DOI: 10.1038/s43018-024-00838-6 A scientist whose discoveries about prostate cancer have led to lifesaving treatments is now shedding light on an emerging and deadlier form of the disease: neuroendocrine prostate...
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What is stereotactic radiation therapy for prostate cancer? How does it compare to other treatments?
by Sathana Dushyanthen and David Kok, The Conversation Comparison of differences between traditional radiotherapy and stereotactic radiotherapy. Credit: Precision Radiation Oncology Prostate cancer is Australia’s most commonly diagnosed cancer. One in six men will be diagnosed by the time they turn 85. Cancers are abnormal groups of cells that grow uncontrollably and start invading neighboring sites. They can also spread to...
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Regulations of m6A and other RNA modifications and their roles in cancer
by Frontiers Journals Credit: Frontiers of Medicine (2024). DOI: 10.1007/s11684-024-1064-8 Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A comprehensive review published in Frontiers of Medicine reveals the significant role of various RNA modifications in cancer development and progression. The review particularly focuses...
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Lymph node-like structures may trigger the demise of cancer tumors
by Johns Hopkins University School of Medicine Tertiary lymphoid structure. Credit: Daniel Shu A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center. The study, published in Nature...
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Does hormone replacement therapy increase cancer risk?
by Huntsman Cancer Institute Credit: Pixabay/CC0 Public Domain For millions of American women, hormone replacement therapy (HRT) has provided relief from side effects of menopause. As the ovaries stop releasing eggs, a woman’s body also stops producing the hormones progesterone and estrogen. This change often affects quality of life due to hot flashes, mood swings, vaginal...
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Performance in physical tests can help manage treatment for metastatic lung cancer
by FAPESP Credit: Unsplash/CC0 Public Domain A study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical tests such as sitting down, standing, and walking can help physicians arrive at a prognosis and approach to treatment. An article on the study is published in...
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Scientists glue two proteins together, driving cancer cells to self-destruct
by Rachel Tompa, Stanford University Medical Center Turning kinase inhibitors into activators of therapeutic genes. Credit: Science (2024). DOI: 10.1126/science.adl5361 Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis. These cells—mainly blood and gut cells—are all replaced with new ones, but the way our bodies rid...
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ACOG Updates Breast Cancer Screening Guidelines
The American College of Obstetricians and Gynecologists (ACOG) has updated its breast cancer screening guidelines, recommending that individuals at an average risk for breast cancer initiate mammography screening at age 40. This change reflects evolving evidence that starting earlier screening yields greater net benefits in reducing breast cancer mortality, particularly for certain racial groups with higher...
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New CAR-T cells offer on-demand control for cancer treatment
Credit: Pixabay/CC0 Public Domain Ludwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells—a type of cancer immunotherapy—that can be switched on to varying degrees of intensity and then switched off on demand with existing drugs. The design and preclinical evaluation of the CAR-T cells, led by Melita Irving and Greta...