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How Do Tapinarof and Roflumilast Creams Fit Into Psoriasis Treatment?

HUNTINGTON BEACH, Calif. — The US Food and Drug Administration (FDA) approvals of tapinarof 1% cream and roflumilast 0.3% cream as treatment options for patients with plaque psoriasis came more than 1 year after the American Academy of Dermatology/National Psoriasis Foundation Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine...

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‘Gift That Keeps Giving’: The Impact of GLP-1 in Asthma

Akshay B. Jain, MD: Welcome back to Medscape at ADA 2024, where Dr James Kim, primary care physician from Calgary, Alberta, will be joining me, Akshay Jain, an endocrinologist from Vancouver, Canada, in deciphering the key highlights at the ADA conference and bringing our own clinical twist into what the relevance would be for people like...

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Revolutionizing cartilage repair: The role of macrophages and hyaluronic acid in healing injuries

by NYU Tandon School of Engineering Researchers found that Intra-articular injections of P15-1 together with high-molecular-weight hyaluronan (HMWHA) improved cartilage repair. In the left image, injections with HMWHA alone produced less robust cartilage repair than the right image, where it was paired with P15-1. Credit: NYU Tandon School of Engineering Injuries of the knee resulting in...

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Data show overdose deaths are down nationally, but up in many Western states

Credit: Pixabay/CC0 Public Domain Despite an encouraging national dip in the past year, overdose deaths are still on the rise in many Western states as the epicenter of the nation’s continuing crisis shifts toward the Pacific Coast, where deadly fentanyl and also methamphetamine are finding more victims. Overdose deaths remain sharply higher since 2019. Many...

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How Are Doctors Using Tirzepatide vs Semaglutide? A Q&A

When prescribing glucagon-like peptide 1 (GLP-1) medications, many physicians prefer tirzepatide over the more well-known semaglutide due to its superior efficacy in weight loss and A1c reduction. Studies indicated that tirzepatide can lead to greater weight loss than semaglutide. Factors like insurance coverage, drug availability, and side effects also influence physicians’ choices, with some patients...

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A telling chart shows how health insurers found a way to boost profits by limiting care for seniors

Adobe You’re reading the web version of Health Care Inc., STAT’s weekly newsletter following the flow of money in medicine. Sign up to get it in your inbox every Monday. The ‘#1 PRIORITY’ The emails from inside a physician practice owned by UnitedHealth Group sounded cheery, but were all business. advertisement One email trumpeted “ADDITIONAL BONUSES!!” for doctors who...

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Semaglutide boosts heart health, weight loss but may lead to gut problems

Semaglutide drugs aid weight loss and heart health but does that come at the expense of gut health? Image credit: Douglas Cliff/Getty Images. The diabetes medication semaglutide — sold under brand names including Ozempic, Wegovy, and Rybelsus — which has also gained popularity as a weight-loss tool, has another significant health benefit, a new meta-analysis suggests. Only Wegovy has...

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Glucose-sensitive insulin with attenuation of hypoglycemia

Abstract The risk of inducing hypoglycaemia (low blood glucose) constitutes the main challenge associated with insulin therapy for diabetes1,2. Insulin doses must be adjusted to ensure that blood glucose values are within the normal range, but matching insulin doses to fluctuating glucose levels is difficult because even a slightly higher insulin dose than needed can...

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Investigating strategies to help clinicians and patients navigate prescription costs

Credit: Unsplash/CC0 Public Domain Brigham researchers reviewed the benefits and limitations of seven strategies that clinicians can use to help their patients navigate high-prescription drugs. These include co-payment cards, patient assistance programs, pharmacy coupons, direct-to-consumer pharmacies, public assistance programs, international online pharmacies, and real-time prescription benefit tools. They developed an algorithm covering how to think...

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Comorbidities Associated With Psoriasis: 5 Things to Know

Psoriasis is an immune-mediated chronic inflammatory skin disease that affects approximately 2%-4% of adults in Western countries. Over the past decade, discovery of the pathogenic pathways in psoriasis has led to a greater understanding of the role psoriasis plays in systemic inflammation and associated comorbidities. Several recent studies have shown that patients with psoriasis have higher rates of comorbid...