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Cutaneous malignant melanoma incidence increasing among the elderly

by Elana Gotkine From 1987 to 2016, there was a considerable increase in the incidence of cutaneous malignant melanoma (CMM) among the elderly in the United States, according to a study published online Oct. 28 in Cancer Screening and Prevention. ADVERTISING Ruofei Du, Ph.D., from Shaanxi University of Chinese Medicine in Xianyang, and colleagues examined CMM incidence trends...

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New resource maps gene-disease links across common conditions, paving the way for personalized medicine

by Hebrew University of Jerusalem Credit: Pixabay/CC0 Public Domain A new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the novel approach of the proteome-wide association study (PWAS), which complements traditional genetic analysis methods like the genome-wide association study (GWAS) by focusing on the effects of genetic...

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Increased psoriasis risk found in cancer patients treated with immune checkpoint inhibitors

by Justin Jackson , Medical Xpress Credit: Estzer Miller on Pixabay Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients with cancer undergoing immune checkpoint inhibitor (ICI) treatments, with implications for other immune-related adverse events. Over the past decade, ICIs have become an increasingly important part...

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Risk of internal bleeding doubles when people on anticoagulants take NSAID painkiller, study finds

by European Society of Cardiology Interactions between non-steroidal anti-inflammatory drugs (NSAIDs) and oral anticoagulants (OACs) that may contribute to excess risk of gastrointestinal (GI) and non-GI bleeding. Credit: European Heart Journal (2024). DOI: 10.1093/eurheartj/ehae795 People who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory...

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New Sexually Transmitted Fungal Infection Emerges in MSM

A dermatophyte known as Trichophyton mentagrophytes genotype VII (TMVII) has been identified as the cause of an emerging sexually transmitted fungal infection in four adults in the United States, according to a paper published in the Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report (MMWR). TMVII is a sexually transmitted fungus that causes genital tinea; the fungus might...

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Erase the trace: New frontiers in scar prevention and skin repair

Peer-Reviewed Publication ELSP image:  Disruptions during wound healing phases (inflammation, proliferation, and remodeling) can result in scar formation. Higher levels of inflammatory markers (TGF-β1, TGF- β2, VEGF) and type 1 collagen are present in scars. Current treatments for scars include pressure garments, corticosteroids, laser therapy, and scar excision. Current research explores Yes-associated protein and harnesses...

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Spironolactone, a blood pressure medication, may help reduce risk of new heart failure

by American Heart Association Spironolactone 50 mg. Credit: Spirono/Wikimedia Commons, CC BY New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack. However, it did not significantly reduce the number of deaths or other severe heart-related events, according to...

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Staggeringly high’ discontinuation rates for GLP-1 drugs like Ozempic or Wegovy

by Kristin Samuelson, Northwestern University Credit: Markus Winkler from Pexels The use of diabetes and weight-loss medications like Ozempic or Wegovy—called GLP-1 drugs—has exploded in recent years, with 12% of U.S. adults having used one despite the high cost, according to a June 2024 poll. What’s less talked about is that 50%–75% of people who start taking these...

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Oakland clinic gets medical device maker to disclose risk of false blood-oxygen reading

by Corinne Purtill, Los Angeles Times Credit: Pixabay/CC0 Public Domain The pulse oximeter, a device that measures the degree to which red blood cells are saturated with oxygen, is one of health care’s most fundamental tools. So when Dr. Noha Aboelata learned that research stretching back decades showed that the devices routinely failed patients with...