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Oral antibiotics and risk of serious cutaneous adverse drug reactions

News Release 8-Aug-2024 JAMA Peer-Reviewed PublicationJAMA Network About The Study: Commonly prescribed oral antibiotics are associated with an increased risk of serious cutaneous adverse drug reactions compared with macrolides, with sulfonamides and cephalosporins carrying the highest risk. Prescribers should preferentially use lower-risk antibiotics when clinically appropriate. Corresponding Author: To contact the corresponding author, David N....

Saliva indicates severity of recurrent respiratory infections in children
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Saliva indicates severity of recurrent respiratory infections in children

August 8, 2024 by Radboud University Senior author Lilly Verhagen, pediatric infectious disease specialist and immunologist at Radboudumc. Credit: RadboudumcA saliva test can more accurately indicate the severity of recurrent respiratory infections in children than the standard blood test. If saliva contains too few broadly protective antibodies, a child is more likely to suffer from...

FDA approves Darzalex Faspro for treating multiple myeloma
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FDA approves Darzalex Faspro for treating multiple myeloma

August 8, 2024 by Lori Solomon The U.S. Food and Drug Administration has approved Johnson & Johnson’s Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation in patients with newly diagnosed multiple myeloma (MM) who are eligible for an autologous stem cell transplant (ASCT). The approval was...

A simple test can predict whether smokers will manage to quit
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A simple test can predict whether smokers will manage to quit

August 8, 2024 by Steinar Brandslet, Norwegian University of Science and Technology Credit: Pixabay/CC0 Public DomainData from nearly 6,000 smokers with cancer show that it may be easier to predict who will stop smoking than was previously thought. It is often important to get cancer patients to quit smoking, but it is not always that...

Many doctors underestimate the pain of IUD insertion for women—the CDC wants to change that
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Many doctors underestimate the pain of IUD insertion for women—the CDC wants to change that

August 8, 2024 by Robin Foster Plenty of women know that having an IUD inserted in their uterus can be an excruciating experience, but new government guidance issued Thursday may soon make the experience less painful for many. For the first time, updated recommendations from the U.S. Centers for Disease Control and Prevention advise doctors...

In Parkinson’s, dementia may occur less often, or later, than previously thought
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In Parkinson’s, dementia may occur less often, or later, than previously thought

August 7, 2024 by American Academy of Neurology Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: WikipediaThere’s some good news for people with Parkinson’s disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course...

Better understanding cerebral palsy pain types could lead to better treatment
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Better understanding cerebral palsy pain types could lead to better treatment

August 7, 2024 by Valerie Goodwin, University of Michigan Descriptive characteristics of adults with cerebral palsy. Credit: JAMA Neurology (2024). DOI: 10.1001/jamaneurol.2024.2443Pain management is an important component of caring for adults with cerebral palsy. However, it’s the least understood comorbidity in the adult cerebral palsy population. A study led by Mark Peterson, Ph.D., M.S., FACSM,...

New study confirms high autism recurrence rates in families with autistic children
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New study confirms high autism recurrence rates in families with autistic children

News Release 7-Aug-2024 Using more comprehensive reporting strategies than in the past, researchers find significantly elevated autism risk among younger siblings Peer-Reviewed PublicationKennedy Krieger Institute image: Rebecca Landa, PhD, CCC-SLP; Vice President, Executive Director for the Center for Autism Services, Science and Innovation (CASSI) Credit: Kennedy Krieger Institute BALTIMORE, August 7, 2024— A study conducted...

Drug bypasses suppressive immune cells to unleash immunotherapy
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Drug bypasses suppressive immune cells to unleash immunotherapy

August 6, 2024 by Marta Wegorzewska, Washington University School of Medicine Immunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body’s healthy cells inadvertently...

FDA approves new therapy for glioma patients for first time in decades
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FDA approves new therapy for glioma patients for first time in decades

August 7, 2024 by Dana-Farber Cancer Institute Glioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Vorasidenib has been approved by the U.S. Food and Drug Administration (FDA) for patients with Grade 2 gliomas with IDH1 or IDH2 mutations. Based on evidence from the INDIGO clinical trial, a global...