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Brain inflammation may be the reason behind muscle fatigue after infection and injury

by Diego E. Rincon-Limas and Aaron N. Johnson, The Conversation Credit: Pixabay/CC0 Public Domain Infectious or chronic diseases such as long COVID, Alzheimer’s disease and traumatic brain injury can cause inflammation in the brain, or neuroinflammation, that weakens muscles. While scientists are aware of this link between inflammation and muscle weakness, the molecules and processes involved have...

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Superior quality cytokines are crucial for advancing immunotherapy development

Sponsored Content by Sino Biological Inc.Reviewed by Olivia FrostDec 16 2024 Cytokines are small, secreted proteins able to pass messages between cells. Members of this superfamily include growth factors, interleukins, chemokines, interferons, colony-stimulating factors, and tumor necrosis factors (TNF).1 Cytokines are produced by a wide range of cell types, including immune cells. In this instance, these...

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Naloxone can temporarily reverse opioid overdose: Why you might need some at home or in your bag

by Shane Darke, The Conversation Credit: Unsplash/CC0 Public Domain Opioids are some of the most widely used and misused drugs in the world. Opioids are central nervous system depressants, meaning they slow down brain activity and relax the muscles. They include the natural products of the opium poppy as well as synthetic (human-made) compounds derived from it. Commonly used opioids...

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Technosphere insulin + insulin degludec noninferior to usual care in T1DM

by Elana Gotkine For adults with type 1 diabetes, a regimen of inhaled Technosphere insulin (TI) plus insulin degludec is noninferior to usual care for glycemic control, according to a study published online Dec. 6 in Diabetes Care. Irl B. Hirsch, M.D., from the University of Washington in Seattle, and colleagues examined a regimen of TI...

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Clopidogrel edges out aspirin in heart procedure recovery

by Justin Jackson , Medical Xpress Credit: CC0 Public Domain Researchers at 37 sites in South Korea have found patients taking clopidogrel after percutaneous coronary intervention (PCI) experienced lower rates of both thrombotic and bleeding events than those taking aspirin. Clopidogrel’s benefits remained consistent regardless of high bleeding risk (HBR) or complex PCI. PCI (also...

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Women Largely Unaware of Anti-Seizure Med Risks, More Education Needed

Pauline Anderson December 11, 2024 161  The majority of women with epilepsy are inadequately educated about the potential risks associated with anti-seizure medications (ASMs), which include teratogenicity and a reduction in the efficacy of hormonal birth control, early results of a new survey suggested. In addition, only about a third of survey respondents indicated that...

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Your Guide to COVID Vaccines for 2024-2025

Kathleen Doheny December 11, 2024 2122 Added to Email Alert Dec. 9, 2024 — The updated COVID vaccines for 2024-2025 are officially here, designed to target the latest variants and offer robust protection — but getting Americans to roll up their sleeves could prove harder than ever. With COVID cases on the decline, many people...

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Bioactive Dressings: Redefining Wound Care Beyond Tradition

By Benedette Cuffari, M.Sc.Reviewed by Danielle Ellis, B.Sc. The limitations of traditional wound careThe power of bioactive dressingsChoosing the right bioactive dressingThe future of wound careReferencesFurther reading The limitations of traditional wound care After an injury has occurred, a complex cascade of biological processes is initiated to support the repair and regeneration of lost or damaged tissue....

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Dual screening in diabetes: Liver fibrosis and eye disease detection

by Karolinska Institutet Credit: Unsplash/CC0 Public Domain New research from Karolinska Institutet in Sweden highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye disease. The study “Screening for advanced liver fibrosis due to metabolic dysfunction-associated steatotic liver disease alongside retina scanning in...

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ACIP updates recommendations for Bexsero MenB-4C vaccine

by Elana Gotkine The Advisory Committee on Immunization Practices (ACIP) recommendations have been updated for the meningococcal serogroup B MenB-4C vaccine (Bexsero), in accordance with the updated U.S. Food and Drug Administration label. The updated recommendations have been published in the Dec. 12 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report....