Peer-Reviewed Publication ELSP image: Disruptions during wound healing phases (inflammation, proliferation, and remodeling) can result in scar formation. Higher levels of inflammatory markers (TGF-β1, TGF- β2, VEGF) and type 1 collagen are present in scars. Current treatments for scars include pressure garments, corticosteroids, laser therapy, and scar excision. Current research explores Yes-associated protein and harnesses...
Category: <span>Clinical Practice</span>
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Spironolactone, a blood pressure medication, may help reduce risk of new heart failure
by American Heart Association Spironolactone 50 mg. Credit: Spirono/Wikimedia Commons, CC BY New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack. However, it did not significantly reduce the number of deaths or other severe heart-related events, according to...
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Staggeringly high’ discontinuation rates for GLP-1 drugs like Ozempic or Wegovy
by Kristin Samuelson, Northwestern University Credit: Markus Winkler from Pexels The use of diabetes and weight-loss medications like Ozempic or Wegovy—called GLP-1 drugs—has exploded in recent years, with 12% of U.S. adults having used one despite the high cost, according to a June 2024 poll. What’s less talked about is that 50%–75% of people who start taking these...
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Oakland clinic gets medical device maker to disclose risk of false blood-oxygen reading
by Corinne Purtill, Los Angeles Times Credit: Pixabay/CC0 Public Domain The pulse oximeter, a device that measures the degree to which red blood cells are saturated with oxygen, is one of health care’s most fundamental tools. So when Dr. Noha Aboelata learned that research stretching back decades showed that the devices routinely failed patients with...
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FDA approves Cobenfy for adults with schizophrenia
by Lori Solomon The U.S. Food and Drug Administration has approved Bristol Myers Squibb’s Cobenfy (xanomeline and trospium chloride), a first-in-class muscarinic agonist, for the treatment of schizophrenia in adults. The oral medication represents the first new class of medicine in several decades and selectively targets M1 and M4 receptors in the brain, without blocking D2 receptors. The approval is...
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Study reveals COVID-19 vaccine safety in patients with atrial fibrillation/flutter
by Korea University College of Medicine Subgroup analyses revealed significantly higher risk of thrombo-embolic events in patients with atrial fibrillation/flutter (AF/AFL) not receiving oral anticoagulants (OACs). COVID-19 vaccination is relatively safe for patients with AF/AFL, especially with concurrent OACs. Credit: Professor Jin Oh Na from Korea University College of Medicine Development of the coronavirus disease...
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How ulcerative colitis can affect the eyes
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD). The underlying inflammation of UC can lead to eye conditions such as scleritis and uveitis. Without treatment, some conditions may lead to vision loss. UC is a chronic condition that primarily affects the large intestine. It is a type of IBD, meaning that inflammation...
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Infographic: Why Malpractice Lawsuits Worry Doctors
Over 40% of physicians in a Medscape survey said they had been sued for alleged malpractice at least once. Annual malpractice premiums for most doctors cost more than $10,000, and around 1 in 3 court awards exceed $500,000. Physicians said improving doctor-patient communications and running lawsuits past a screening panel could help. This infographic shows...
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Oral Semaglutide 25-mg Dose May Provide Most Benefit
SAN ANTONIO — Oral semaglutide 25 mg appears to be just as effective in promoting weight loss and other beneficial outcomes as are the investigational 50-mg oral dose and the injectable 2.4-mg dose (Wegovy), in new research. Data from Novo Nordisk’s OASIS 4 trial suggest that “oral semaglutide 25 mg may represent an efficacious option...
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Veterans study finds virtual mental health care can significantly reduce suicide
by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain Boston University School of Public Health research suggests that virtual mental health care may significantly reduce suicide-related events (SREs) among veterans recently released from service. For every 1% increase in virtual mental health visits, there was a 2.5% decrease in SREs. Mental health care has...