MASS GENERAL BRIGHAM Rachel L. Wasserman, PharmD, of the Department of General Internal Medicine at Brigham and Women’s Hospital, is the lead author and David W. Bates, MD, medical director of Clinical and Quality Analysis for Mass General Brigham and Co-Director of the Center for Artificial Intelligence and BioInformatics for Mass General Brigham, is the...
Category: <span>Clinical Practice</span>
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Prostate Meds Tied to Reduced Risk for Lewy Body Dementia
Certain medications that are used to treat benign prostatic hyperplasia (BPH) are associated with a reduced risk for dementia with Lewy bodies (DLB), the second most common neurodegenerative type of dementia after Alzheimer’s disease. Investigators found older men taking alpha-1 blockers terazosin, doxazosin, or alfuzosin (Tz/Dz/Az) were 40% less likely to develop DLB than those...
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Reduced Risk for Peripheral Neuropathy Tied to Diabetes Medication
MONTREAL —Tirzepatide (Mounjaro, Eli Lilly), the dual gastric inhibitory polypeptide–glucagon-like peptide 1 (GIP–GLP-1) receptor agonist that has shown significant benefits in diabetes and obesity, may also help prevent diabetic peripheral neuropathy (DPN), new research suggests. In a large database analysis of patients with type 2 diabetes, those taking tirzepatide had a significantly reduced risk for...
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Turmeric and black pepper supplements linked to liver injury in some people
Research shows that turmeric supplements may have adverse effects. Santiago Urquijo/Getty ImagesThe spice turmeric is a popular food supplement due to a molecule it contains called curcumin, which acts as a strong antioxidant.it is also thought that it could be used to treat or prevent inflammatory conditions.Turmeric’s use has grown in popularity in the past...
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Urgent recall of blood pressure medications over fear pills can cause irregular heart beat, cardiac arrest
By JAMES CIRRONE FOR DAILYMAIL.COM A whopping 135 batches of blood pressure medication have been recalled over fears that the pill capsules won’t properly dissolve when ingested by patients. Glenmark Pharmaceuticals initiated a voluntary recall of 114 batches of 750 mg Potassium Chloride in bottles containing 100 and 500 pills, with all of the specific...
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Pain doesn’t belong on a scale of zero to 10
KFF Health NewsJul 2 2024 Over the past two years, a simple but baffling request has preceded most of my encounters with medical professionals: “Rate your pain on a scale of zero to 10.” I trained as a physician and have asked patients the very same question thousands of times, so I think hard about...
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The role of cytokines as key drivers of autoimmune pathogenesis
Sponsored Content by ACROBiosystemsReviewed by Aimee MolineuxJul 1 2024 Cytokines are important protein mediators of immunity, inflammation, and cell behavior. Given that these are the main biological processes involved in autoimmunity, there is evidence that cytokines play a crucial role in the pathogenesis of autoimmune diseases. The role of cytokines in AS, PsA and SScThe...
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Benefits of thymectomy in treating myasthenia gravis
JULY 2, 2024 by Ellen Goldbaum, University at Buffalo T cell development in the thymus. Credit: Neurology (2024). DOI: 10.1212/WNL.0000000000209482The first-ever randomized study of the removal of the thymus gland in treating myasthenia gravis was conducted in 2016. Led by Gil I. Wolfe, MD, SUNY Distinguished Professor and the Irvin and Rosemary Smith Professor of...
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Sound stimulation aids saccular dysfunction with Meniere disease
JULY 2, 2024 by Lori Solomon and Marianne Madeiros s Sound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with definitive Meniere disease, according to a study published online June 24 in Acta Oto-Laryngologica. Michihiko Sone, M.D., Ph.D., from the Nagoya University Graduate...
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Spatial Transcriptomics in Neuroscience and Neurological Disorders
By Matthew AdamsReviewed by Danielle Ellis, B.Sc. Spatial transcriptomics is a new tool that may prove key to increasing our understanding of tissues and the cellular processes at work in a 3D space. This article describes the basic principles of spatial transcriptomics, alongside its application in neuroscience both cognitively and clinically. Image Credit: PeopleImages.com –...