Miriam E. Tucker July 13, 2023 Should pharmacologic treatment of type 2 diabetes start with combination therapy or metformin monotherapy, adding other agents over time? This question was debated at the recent American Diabetes Association 83rd Scientific Sessions by two well-known clinician-researchers in the diabetes world. Ralph A. DeFronzo, MD, argued for combination therapy at the time of diagnosis,...
Category: <span>Diabetes</span>
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Studies Implicate GLP-1 Agonists in Progression of Diabetic Retinopathy
Ellen Kurek August 03, 2023 SEATTLE — A family of blockbuster drugs for managing blood glucose — and now for promoting weight loss — has been linked to exacerbation of macular disease that frequently accompanies diabetes, new data show. Two studies presented at the 2023 annual meeting of the American Society of Retina Specialists have found that...
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Experimental insulin implant uses electricity to control genes
Lilly Tozer An insulin crystal viewed under a light microscope. People with type 1 diabetes do not make enough insulin, which helps to control blood sugar levels. Credit: Alfred Pasieka/Science Photo Library Genetically engineered human cells that produce insulin when stimulated by a small electric current could one day be used to develop better treatments...
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World-first human trial: Experimental hookworm infection led to improvements in type 2 diabetes patients
by James Cook University Impact of experimental hookworm infection on body mass. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-40263-4 A world-first human trial at James Cook University using live hookworms to combat diseases such as type 2 diabetes has proven successful—sparking interest in staging a larger-scale international trial. Dr. Doris Pierce from JCU’s Australian Institute of Tropical Health and...
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Researchers develop 3D printed bandage that delivers innovative treatment for diabetic foot ulcers
by Queen’s University Belfast Credit: Queen’s University Belfast Researchers from Queen’s University Belfast have designed a new 3D printed bandage, known as a scaffold, which presents an innovative method of treatment to heal diabetic foot ulcers (DFUs). The research is the first of its kind and is a breakthrough for diabetes management. The findings have been published in...
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33% of Type 1 Diabetes Patients Insulin-Free With Stem Cells
Miriam E. Tucker July 03, 2023 SAN DIEGO — An investigational allogeneic stem cell–derived pancreatic islet cell replacement therapy (VX-880, Vertex Pharmaceuticals) continues to show promise as a treatment for type 1 diabetes, according to the latest data, from six patients thus far. Two of the six are insulin-independent beyond 1 year after receiving the VX-880 infusions,...
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‘Artificial Pancreas’ for All Type 1 Diabetes Pregnancies?
Marlene Busko July 05, 2023 SAN DIEGO – In the largest randomized controlled trial of an automated insulin delivery (AID) system (hybrid closed-loop) versus standard insulin delivery in pregnant women with type 1 diabetes, the automated CamAPS FX system prevailed. The percentage of time spent in the pregnancy-specific target blood glucose range of 63-140 mg/dL...
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These lollipops could ‘sweeten’ diagnostic testing for kids and adults alike
Peer-Reviewed Publication AMERICAN CHEMICAL SOCIETY IMAGE: CANDYCOLLECT, PICTURED HERE, COULD REPLACE THROAT SWABS TO DIAGNOSE RESPIRATORY ILLNESSES, INCLUDING STREP THROAT CREDIT: ADAPTED FROM ANALYTICAL CHEMISTRY, 2023, A lollipop might be a sweet reward for a kid who’s endured a trip to the doctor’s office, but now, this candy could make diagnostic testing during a visit...
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Cagrilintide With Semaglutide: A Way to Prevent Diabesity?
Marlene Busko June 24, 2023 SAN DIEGO — Coadministration of the long-acting amylin analog cagrilintide plus the glucagon-like peptide-1 (GLP-1) agonist semaglutide, dubbed CagriSema, resulted in significantly greater weight loss, along with improved measures of glucose control, than either agent alone, in a small, short phase 2 trial of patients with type 2 diabetes. Juan P. Frias, MD,...
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Plant extract found to stabilize blood sugar levels in type 2 diabetics
By Paul McClure July 10, 2023 A clinical study has found that compounds found in the dahlia flower petals act on the brain to improve blood glucose levels in type 2 diabetics Depositphotos Researchers have discovered a plant extract that targets the glucose-regulating regions of the brain that are inflamed in type 2 diabetics, improving blood...