In a rat model, the discs became stiffer and changed shape earlier than normalPeer-Reviewed Publication UNIVERSITY OF CALIFORNIA – SAN DIEGO THE HIERARCHICAL STRUCTURE OF THE INTERVERTEBRAL DISC (APPROXIMATELY 45–55 MM DIAMETER IN THE HUMAN LUMBAR SPINE AND 2.5–5 MM IN THE RAT COCCYGEAL SPINE) IS COMPOSED OF THE OUTER FIBER-REINFORCED ANNULUS FIBROSUS AND INNER...
by University of Barcelona Proposed mechanistic model for the hepatic effects of Gdf15 deficiency on fibrosis, gluconeogenesis and fatty liver via the TGF-β1-SMAD3 pathway. Credit: Metabolism (2024). DOI: 10.1016/j.metabol.2023.155772A study led by the University of Barcelona and the Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders (CIBERDEM) reveals how a new mechanism could improve...
By LUNENFELD-TANENBAUM RESEARCH INSTITUTE Researchers have conducted a study revealing that post-meal insulin surges might indicate good metabolic health, challenging the previously held belief that they are harmful. The study, which focused on long-term cardiometabolic implications in new mothers, found that higher corrected insulin response (CIR) levels are associated with better beta-cell function and a...
Peer-Reviewed Publication UNIVERSITY OF BRISTOL A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins, according to the findings of a new University of Bristol-led study. The study, published in eBioMedicine, is the first to show that weight loss in people recently diagnosed with diabetes can change...
By Dr. Chinta SidharthanJan Reviewed by Lily Ramsey, LLMIn a recent study published in Communications Biology, a team of scientists investigated how type 2 diabetes and genetic susceptibility to the disease impacted the severity of and mortality risk associated with coronavirus disease 2019 (COVID-19) using data from the United Kingdom (U.K.) Biobank. Study: Type 2...
By Neha Mathur Reviewed by Lily Ramsey, LLMIn a narrative review published recently in the Nutrients Journal, researchers reviewed evidence supporting adzuki bean (Vigna angularis) supplementation to prevent and manage type 2 diabetes (T2D). Study: The Potential of the Adzuki Bean (Vigna angularis) and Its Bioactive Compounds in Managing Type 2 Diabetes and Glucose Metabolism:...
By Pooja Toshniwal PahariaJan 22 2024 Reviewed by Danielle Ellis, B.Sc.The researchers of a recent study published in Nature Metabolism investigated the relationship between milk consumption and type 2 diabetes (T2D) among lactase non-persistent (LNP) individuals. Study: Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes. Image Credit:...
by University of Eastern Finland Both total body fat mass and abdominal fat cause hyperglycemia, hyperinsulinemia, and insulin resistance, with abdominal fat doubling the risk of metabolic dysfunction. However, light physical activity can significantly reduce total body fat mass and insulin resistance. Credit: Andrew AgbajeHigh fat mass in adolescence causes insulin resistance, which can lead to...
by Vanderbilt University Medical Center Graphical abstract. Credit: Diabetes (2023). DOI: 10.2337/db23-0356A recent study published in the journal Diabetes demonstrates that a glucagon-like peptide-1 receptor (GLP-1R) agonist, a member of a class of medication used to treat type 2 diabetes and obesity, can lead to a rapid improvement in insulin sensitivity. Insulin sensitivity is how responsive...
by UT Southwestern Medical Center Credit: Unsplash/CC0 Public DomainA two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers. Published in Circulation, the study found that the new strategy...
