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Researchers studying new way to heal diabetic wounds by activating ‘hidden’ mechanism in the body
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Researchers studying new way to heal diabetic wounds by activating ‘hidden’ mechanism in the body

by Indiana University School of Medicine Graphical abstract. Credit: Molecular Therapy (2022). DOI: 10.1016/j.ymthe.2022.09.002 Researchers at Indiana University School of Medicine are looking for ways to heal wounds by using a healing protein that is active in fetuses, but largely inactive in adults and absent in diabetic adults. “We already know from previous studies at other institutions...

Afternoon or evening physical activity is linked to reduced insulin resistance, better control of blood sugar
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Afternoon or evening physical activity is linked to reduced insulin resistance, better control of blood sugar

by Diabetologia Credit: CC0 Public Domain A new study published in Diabetologia finds that afternoon or evening physical activity is associated with reduced insulin resistance (and thus better blood sugar control) when compared with an even distribution of physical activity through the day. Morning physical activity offered no advantages, concluded the study by Dr. Jeroen van der...

Research unlocks the circuitry of diabetes
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Research unlocks the circuitry of diabetes

by Sanford Burnham Prebys Medical Discovery Institute A pancreatic islet from a mouse in a typical position, close to a blood vessel; insulin in red, nuclei in blue. Credit: Generated in the Solimena lab, Paul Langerhans Institute Dresden Research led by Pamela-Itkin-Ansari, Ph.D., and Randal Kaufman Ph.D., has mapped out a network of biochemical interactions...

Diabetes-causing gene can be regulated like a rheostat
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Diabetes-causing gene can be regulated like a rheostat

by Center for Genomic Regulation  Image of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory element has been knocked out in this mouse, resulting in changes to beta cell function that cause diabetes. Credit: Miguel A Garriga/CRG Researchers at the Centre for Genomic Regulation (CRG)...

South Asian women get diabetes at higher rates. A study aims to fight those stats with exercise
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South Asian women get diabetes at higher rates. A study aims to fight those stats with exercise

by Lisa Schencker  Credit: Unsplash/CC0 Public Domain Like many moms, Asmita Patel has struggled to find time to exercise in recent years. Between working, taking care of her children, caring for relatives and shuttling her kids to activities, she didn’t work out much. That changed, however, last month when the Niles woman and her 13-year-old...

5 unusual symptoms of diabetes
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5 unusual symptoms of diabetes

Diabetes is a condition that can affect the whole body and cause a variety of symptoms. Many common and unusual symptoms occur due to uncontrolled high blood sugars. Recognizing symptoms early on can be key to successfully treating and managing the condition. Diabetes describes a group of health conditions that impairs how the body processes sugar...

CDF15 cytokine, a promising therapeutic target against type 2 diabetes
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CDF15 cytokine, a promising therapeutic target against type 2 diabetes

UNIVERSITY OF BARCELONA IMAGE: FROM LEFT TO RIGHT, EMMA BARROSO, MARTA MONTORI, DAVID AGUILAR-RECARTE, XAVIER PALOMER, LUCÍA PEÑA, GAIA BOTTERI, MANUEL VÁZQUEZ-CARRERA, MOHAMMAD ZAREI AND JAVIER PIZARRO DELGADO. CREDIT: UNIVERSITY OF BARCELONA A team led by Professor Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine (IBUB) of the UB, has...

Switching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling
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Switching tracks: Changing the trafficking of the glucagon receptor in the liver regulates its metabolic signaling

by Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)  Stained liver cells. Credit: Karsten Motzler A group of researchers from the Helmholtz Munich Institute for Diabetes and Cancer (IDC) have unraveled a new strategy to alter glucagon receptor signaling in the liver by changing its intracellular trafficking. Glucagon is a peptide hormone, that...

New islet transplant method leads to insulin independence
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New islet transplant method leads to insulin independence

by Perelman School of Medicine at the University of Pennsylvania A pancreatic islet from a mouse in a typical position, close to a blood vessel; insulin in red, nuclei in blue. Credit: Generated in the Solimena lab, Paul Langerhans Institute Dresden More than half of the most seriously affected type 1 diabetes patients achieved years...