by Ellen Goldbaum, University at Buffalo Efficacy and adverse events by treatment and mode dose taken. Forest plot shows the rate and adjusted hazard ratios (HRs) of outcomes by strata of mode dose of pioglitazone compared with placebo, for stroke/myocardial infarction, new-onset diabetes, weight gain, heart failure and bone fracture. Lower doses of pioglitazone appear...
by University of Leeds Microscopy image showing human muscle cells with nuclei in blue, and stress caused by the ceramide stress signals shown in red. Credit: Lee Roberts Increased levels of blood fats in people with type 2 diabetes and obesity are more harmful than previously thought, a new study has found. In patients with metabolic...
by Emily Caldwell, The Ohio State University Insulin injections help with management of type 1 and type 2 diabetes. Ohio State researchers have developed a nanomaterial that may improve insulin’s effects on the nervous system. Credit: Shutterstock.com There may be a way in the future to enhance diabetes treatment—with better control of blood sugar and...
Marlene Busko, for Medscape March 24, 2022 Researchers published the study covered in this summary on Research Square as a preprint that has not yet been peer reviewed. Key Takeaways Data from five sequential National Health and Nutrition Examination Survey (NHANES) reports using US population samples in 2009-2018 showed each 1-unit increase in serum levels of vitamin D3 (25-hydroxyvitamin...
UNIVERSITY OF MINNESOTA IMAGE: RESEARCHERS AT THE UNIVERSITY OF MINNESOTA TWIN CITIES AND MAYO CLINIC WERE ABLE TO STORE TINY DROPLETS ENCAPSULATED WITH PANCREATIC ISLET CELLS AT VERY LOW TEMPERATURES FOR UP TO NINE MONTHS AND THEN USE NOVEL REWARMING TECHNIQUES TO BRING THEM BACK TO THEIR ORIGINAL STATE BEFORE TRANSPLANTATION. SHOWN IS ONE APPROACH...
CONCORDIA UNIVERSITY IMAGE: KERRI DELANEY (LEFT) AND SYLVIA SANTOSA: “THE BIG QUESTION IS, HOW DO THE DIFFERENT FAT DEPOTS UNIQUELY CONTRIBUTE TO THE DEVELOPMENT OF DIABETES, AND IS THIS CONTRIBUTION DIFFERENT IN MEN AND WOMEN? CREDIT: CONCORDIA UNIVERSITY Over the past four decades, global cases of Type 2 diabetes mellitus have skyrocketed. According to the World...
Many people with diabetes have times when they sweat too much, too little, or at odd times. Diabetes can make it difficult for a person’s body to maintain a steady temperature and produce the right amount of sweat to keep the body cool. Reasons for this include hormonal imbalances, cardiovascular factors, and stress. Diabetes can affect...
New research explores the health benefits of the so-called Nordic diet. Morten Falch Sortland/Getty Images Researchers investigated the health effects of a healthy Nordic diet (HND) using metabolic analysis. They found that the diet positively affects glucose metabolism, cholesterol, and cardiometabolic risk. They conclude that metabolic analysis is an effective way to assess dietary outcomes....
by University of Illinois at Chicago Credit: Nature Reviews Endocrinology (2022). DOI: 10.1038/s41574-022-00638-x A University of Illinois Chicago team has summarized research on intermittent fasting to provide insights into its effects on the body and to provide advice for incorporating these diets in everyday life. They have also presented recommendations for future research into these popular diet...
Researchers examined the effect moderate drinking may have related to new-onset type 2 diabetes among nearly 312,400 adults from the UK Biobank who self-reported themselves as regular alcohol drinkers. During an average of nearly 11 years of follow-up, about 8,600 of the adults in the study developed type 2 diabetes. The analysis found: Consuming alcohol with meals...
