by University of Leeds Credit: CC0 Public Domain For more than 30 years, scientists have been trying to unravel the mystery of how a key biological molecule self assembles into a rogue protein-like substance known as amyloid, which is thought to play a role in the development of type 2 diabetes—a disease that affects 300...
Category: <span>Diabetes</span>
Researchers identify new method for stimulating signaling to improve metabolic health and possibly treat obesity
by Greg Glasgow, CU Anschutz Medical Campus Credit: CC0 Public Domain Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates...
Culinary medicine education program shows positive outcomes for low-income patients with diabetes
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON A culinary medicine curriculum had a positive impact on certain biometric and diet-related behavioral and psychosocial outcomes among low-income, food-insecure patients with type 2 diabetes participating in a clinic-led food prescription program, according to researchers with The University of Texas Health Science Center at Houston (UTHealth Houston)....
Reprogramming a patient’s immune cells to heal the pancreas and restore the ability to make insulin
by Tyrel Linkhorn, University of Toledo Dr. Juan Jaume’s promising research could revolutionize management of a disease affecting an estimated 1.6 million Americans. Credit: University of Toledo Promising research from The University of Toledo suggests it might be possible to cure Type I diabetes by reprogramming a patient’s own immune cells to heal the pancreas...
When it comes to obesity, the problem isn’t an excess of fat but its loss of function, researchers argue
by Cell Press The hallmarks of adipose tissue dysfunction. Credit: Sakers et al./Cell Obesity is known to cause cardiometabolic diseases like hypertension and diabetes but attributing these diseases to merely an overabundance of fat is a simplification. On a basic level, fat acts as a receptacle to store energy, but upon a closer look it...
Optimizing indoor light conditions to mimic the natural light-dark cycle could help mitigate adverse metabolic effects
by Diabetologia Credit: Unsplash/CC0 Public Domain A new study published in Diabetologia finds that the timing of exposure to bright light can have a significant influence on postprandial (post-meal) glucose metabolism, thermoregulation, and energy expenditure during sleep in overweight, insulin-resistant adults. The research was conducted by Jan-Frieder Harmsen, Patrick Schrauwen, and colleagues at the Department of Nutrition...
New diabetes targets could allow protection of pancreatic beta cells
by Children’s Hospital Boston Beta cells (green) produce the hormone insulin. Raised levels of micro RNA 200 are harmful. Credit: Masur / Wikimedia Commons A central feature of type 1 diabetes is loss of the pancreatic beta cells that make insulin. Researchers led by Paolo Fiorina, MD, Ph.D., of Boston Children’s Hospital and Francesca D’Addio,...
Scripps Research scientists unveil promising new approach to diabetes prevention
SCRIPPS RESEARCH INSTITUTE IMAGE: A SCRIPPS RESEARCH TEAM FOUND A COMPOUND THAT PROTECTS AGAINST DIABETES-LIKE METABOLIC CHANGES IN OBESE MICE, INCLUDING THE REDUCTION IN LIVER FAT DEPOSITS OF TREATED OBESE MICE (RIGHT) COMPARED TO UNTREATED (LEFT). CREDIT: SCRIPPS RESEARCH LA JOLLA, CA—A team of scientists from Scripps Research has conducted promising early tests of a...
Connecting obesity, diabetes and the immune system using bioinformatics
Clues suggest anti-inflammatory macrophages are different in people with diabetes. The link between obesity and illness, particularly type 2 diabetes, is well known. Yet researchers are actively working to understand what it is about fat tissue that leads to metabolic disease. Studies in mice have shown that an increase in immune cells called macrophages in fat tissue...
Sweet pressure—scientists discover link between high blood pressure and diabetes
by University of Bristol Credit: CC0 Public Domain The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar) has finally been cracked by an international team led by the universities of Bristol, UK, and Auckland, New Zealand. The important new discovery has shown...