by University of Birmingham Credit: CC0 Public Domain A study led by the University of Birmingham has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS). The research findings also show that women with PCOS have twice the risk of developing...
Category: <span>Diabetes</span>
Enzyme driving insulin resistance in liver and may represent promising therapeutic target
by Marcela Quintanilla Dieck, Massachusetts General Hospital Graphical abstract. Credit: DOI: 10.1016/j.celrep.2021.109785 A central feature of type 2 diabetes is an inability of the body’s cells to respond to insulin, a hormone that keeps blood glucose levels normal. Critical to this balance is the liver, which both stores and manufactures glucose depending on the body’s need....
New scientific resource will help uncover the genetic underpinnings of type 2 diabetes
by Massachusetts General Hospital Credit: Unsplash/CC0 Public Domain Many variants in the human genome have been linked to type 2 diabetes, but because most do not lie within genes that code for proteins, it’s unclear how they might cause disease. Now an international team, including investigators at Massachusetts General Hospital (MGH), has developed a resource to...
New insights into actions of insulin and their potential impact in treating diabetes
TATA INSTITUTE OF FUNDAMENTAL RESEARCH Insulin is one of the most well known hormones in the human body for its role in regulating blood glucose. While its absence or inaction causes diabetes (Type-I and Type-II), it is also associated with several metabolic disorders such as obesity, hypertension, cancer, and aging. Levels of insulin, produced by...
Gene editing can turn storage fat cells into energy-burning fat cells
by UT Southwestern Medical Center Lavanya Vishvanath, Senior Research Associate and Rana Gupta, Ph.D. in the research lab. Credit: UT Southwestern Medical Center A team of researchers at UT Southwestern Medical Center’s Touchstone Diabetes Center have successfully used CRISPR gene editing to turn fat cells normally used for storage into energy-burning cells. “It’s like flipping a switch. We removed the ‘brake’ on...
Type 2 diabetes drug trial uses patient experience to find their best drug
by University of Exeter Credit: CC0 Public Domain An innovative trial which invited people to take three drugs in turn, then choose their preferred option, has generated insights into which type 2 diabetes drug is best to prescribe to individuals. Led by the University of Exeter and funded by the Medical Research Council, the TriMaster trial presents today...
What are ideal blood sugar levels for preventing repeat strokes, heart attacks?
MINNEAPOLIS – Blood sugar control has always been important for people with diabetes when it comes to preventing a stroke. But a new study finds for people with diabetes who have a stroke, there may be an ideal target blood sugar range to lower the risk of different types of vascular diseases like a stroke or...
Research bolsters link between diabetes and Alzheimer’s disease
by University of Nevada, Las Vegas Credit: Pixabay/CC0 Public Domain A team of UNLV neuroscientists has strengthened the link between Type II diabetes and Alzheimer’s disease. In a study published in the September issue of the journal Communications Biology, researchers show that chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory networks. “Diabetes is a...
Seemingly healthy levels of liver fat can trigger type 2 diabetes, UK study suggests
by Diabetologia Credit: CC0 Public Domain New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD), held online this year, found that the amount of fat stored in the liver is higher in people with type 2 diabetes (T2D), whatever their BMI. It also suggested that levels of liver fat currently...
People of normal weight with type 2 diabetes can achieve remission by losing weight
by Diabetologia Credit: Unsplash/CC0 Public Domain New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD), held online this year, found that contrary to the perceived wisdom, people of normal weight with type 2 diabetes (T2D) can reverse the condition through substantial weight loss. Eight of the 12 participants achieved remission...