Journal of the American Geriatrics Society Research Summary AMERICAN GERIATRICS SOCIETY One in four people aged 65 or older has diabetes. The disease is the seventh leading cause of death in the United States and a major contributor to heart disease. Experts have recommended that the best way to slow the progression of diabetes–and help...
Category: <span>Diabetes</span>
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The regulation of glycemia after stroke improves neurological recovery in diabetes
In a study in mice, researchers at Karolinska Institutet have discovered a new potential therapeutic approach to facilitate neurological recovery in people with diabetes suffering from a stroke. The treatment strategy is based on the chronic normalization of hyperglycemia after stroke. The scientists hope that these new results, presented in the scientific journal Diabetes, open...
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GLP-1-based treatment of diabetes does not cause pancreatitis
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES About 50,000 Danish diabetic patients are treated with GLP-1-based medicine. GLP-1 is a hormone that reduces the blood sugar and inhibits the appetite, and it is a frequent treatment for type 2 diabetes and obesity. A known side effect of this particular treatment is that...
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New indication of a link between Alzheimer’s and diabetes
by Forschungszentrum Juelich Pathological protein clumps are characteristic of a series of diseases, such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. Scientists at Forschungszentrum Jülich, Heinrich Heine University Düsseldorf, and Maastricht University have now used cryo-electron microscopy to obtain a sharp image for the first time of how individual molecules are arranged in...
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First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes
Study reveals previously unknown protein that helps proinsulin fold and opens new avenues for diabetes research SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study,...
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Bone health declining in U.S. adults with and without prediabetes
(HealthDay)—The bone health of adults older than 40 years of age is declining for individuals both with normal glucose regulation and prediabetes, according to a study recently published in Diabetes Care. Chi Chen, M.D., from the Shanghai Jiao Tong University School of Medicine, and colleagues used data from the U.S. National Health and Nutrition Examination...
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Insulins available at US pharmacies are consistent with product labeling
by JDRF JDRF, the American Diabetes Association (ADA), and The Leona M. and Harry B. Helmsley Charitable Trust, announce the results of a study examining the consistency and potency of insulin purchased at U.S. retail pharmacies. The study, led by University of Florida researcher Timothy Garrett and published in Diabetes Care, found all human and...
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Type 2 diabetes linked to worse cognitive performance after a stroke
by American Heart Association People with Type 2 diabetes, but not those with prediabetes, had worse cognitive performance three to six months after a stroke than those with normal fasting blood sugar levels, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association....
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Study confirms diabetes type 3c as early manifestation of pancreatic cancer
by The Spanish National Cancer Research Centre As biomedical sciences incorporate increasingly sophisticated methodologies and technologies, the understanding of diseases improves. Diabetes is a clear example, since new classifications are being added to the traditional classification into type 1 and type 2 diabetes; these new classifications are based on genetic and molecular characteristics that improve...
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Single-cell RNA seq developed to accurately quantify cell-specific drug effects in pancreatic islets
by CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types. Among those are beta cells,...