Category: <span>Diabetes</span>

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Adipocyte glucocorticoid receptors play a role in developing steroid diabetes

Steroids act on adipocyte glucocorticoid receptors (GRs) :Activation of adipocyte GRs restricted healthy adipose expansion, causing insulin resistance, liver steatosis, and eventually diabetes. Credit: Osaka University Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout...

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How diabetes causes muscle loss

Diabetes mellitus is associated with various health problems including decline in skeletal muscle mass. A research group led by Professor Wataru Ogawa at the Kobe University Graduate School of Medicine revealed that elevation of blood sugar levels leads to muscle atrophy and that two proteins, WWP1 and KLF15, play key roles in this phenomenon. These...

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Quality of overall diet is key to lowering type 2 diabetes risk

Consistent with studies in other populations, findings from the first local study, The Singapore Chinese Health Study, conducted by researchers in the National University of Singapore’s (NUS) Saw Swee Hock School of Public Health and Duke-NUS Medical School, have shown that a high-quality diet defined by low intake of animal foods such as red meat,...

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Type 2 diabetes risk up with PCOS regardless of BMI

(HealthDay)—Irrespective of age and weight, women with polycystic ovary syndrome (PCOS) have an increased risk for type 2 diabetes, according to a study published online Jan. 31 in Diabetes Care. Nadira S. Kakoly, M.P.H., from Monash University in Melbourne, Australia, and colleagues estimated nationwide incidence rates and predictors of type 2 diabetes using data from...

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Vitamin D could lower the risk of developing diabetes

CLEVELAND, Ohio (January 30, 2019)–The benefits of vitamin D in promoting bone health are already well known. A new study out of Brazil suggests that vitamin D also may promote greater insulin sensitivity, thus lowering glucose levels and the risk of developing type 2 diabetes. Results are published online today in Menopause, the journal of...

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New hope for stem cell approach to treating diabetes

Scientists working to develop more effective treatments for diabetes are turning to stem cells. Such cells can be transformed into cells that produce insulin, the hormone that controls blood sugar. But there’s a major challenge: the amount of insulin produced by theses cells is difficult to control. Researchers at Washington University School of Medicine in...

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Possible link between rotavirus vaccine and decline in type 1 diabetes

A drop in the number of young children diagnosed with type 1 diabetes could be associated with the introduction of routine rotavirus vaccination of Australian infants, according to a new study by Melbourne researchers. The immune-mediated destruction of insulin-producting islets in the pancreas is the cause of type 1 diabetes. Still from WEHI-TV animation ‘Insulin...

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Leaving two-hour gap between dinner and bedtime may not affect blood glucose – diabetes – patient education

Leaving a two-hour gap between the last meal of the day and bedtime doesn’t seem to be associated with any discernible difference in blood glucose levels among healthy adults over the long term, suggests Japanese research published in the online journal BMJ Nutrition, Prevention & Health. Credit: CC0 Public Domain Avoiding eating a meal or...

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Using genetics of human fat cells to predict response to anti-diabetes drugs

Predicting Response to Anti-Diabetes Drugs Credit: Mitchell Lazar lab, Metabolism in the Perelman School of Medicine at the University of Pennsylvania Drugs called thiazolidinediones (TZDs) reverse insulin resistance in patients with type 2 diabetes by targeting the activity of a receptor protein. However, an array of side effects, including weight gain, edema, and high cholesterol,...

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Statin therapy reduces risk for diabetic retinopathy in T2DM

(HealthDay)—For Taiwanese patients with type 2 diabetes and dyslipidemia, statin therapy is associated with a reduced risk for diabetic retinopathy, according to a study published online Jan. 10 in JAMA Ophthalmology. Eugene Yu-Chuan Kang, M.D., from the Chang Gung Memorial Hospital in Taoyuan, Taiwan, and colleagues examined the correlation between statin therapy and development of...