by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Credit: Pixabay/CC0 Public Domain Today in the United States, about two out of every 1,000 people live with kidney failure. For every one white person who develops the disease, three Black people do. Kidney failure, also known as end-stage renal failure or end-stage kidney disease, is the irreversible...
by Greg Williams, NYU Langone Health Credit: Pixabay/CC0 Public Domain Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found. Led by researchers at NYU Langone Health, a new study pinpointed key Hox genes, specific to each location in the body, as the controllers...
By Bronwyn Thompson March 19, 2023 Scientists unlock more of the genetic code behind depression Depositphotos Depression is incredibly complex, highly individual and most often linked to a cache of other triggers and comorbidities. But in 2021, a look at 1.2 million people found 178 gene variants linked to major depressive disorder (MDD) and confirmed that our...
by Justin Jackson , Medical Xpress GRS performance. a, Prediction performance of three GRSs across ancestry groups for FEV1/FVC shown as the s.d. change in FEV1/FVC per s.d. increase in GRS for individuals in the UK Biobank grouped according to ancestry. Sample sizes: AFR, n = 4,227; AMR, n = 2,798; EAS, n = 1,564; and EUR, n = 320,656. b, Prediction performance...
by The Mount Sinai Hospital Daniel Greene, PhD, and colleagues used a computational approach to identify previously unknown genetic causes of three rare diseases: primary lymphedema, thoracic aortic aneurysm disease, and congenital deafness. In this microscopy image of cells, a mutated form of a protein called ERG, which is present in some lymphedema patients, is...
UNIVERSITY OF MALTA IMAGE: STUDY FIRST AUTHOR DR. REBECCA BORG AND LEAD INVESTIGATOR PROF. RUBEN CAUCHI HOLDING A VIAL WITH FRUIT FLIES (PHOTO BY CHRIS SANT FOURNIER). CREDIT: CHRIS SANT FOURNIER University of Malta researchers have discovered a potential new drug target for amyotrophic lateral sclerosis (ALS), according to a new study published in the Neurobiology of Aging journal....
by Medical College of Georgia at Augusta University Yuqing Huo, MD, PhD, (left) and Qian Ma, PhD. Credit: Michael Holahan, Augusta University The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood...
Reviewed by Emily Henderson, B.Sc. Mar 13 2023 University of Queensland researchers have contributed to the largest ever genetic study of endometriosis, finding new data about the variants that increase risk of the disease. The study found genetic risk factors for endometriosis are also associated with other chronic pain types such as migraine, back pain and multi-site...
by Boston University School of Medicine Sample characteristics for the variables examined in this study. A–C Distribution of total years of play, age at death, and log AT8 histochemical quantification, respectively, for RHI, CTE-L, and CTE-H sample groups. D, E Distribution of age at death for each sample group broken out into risk allele groups for APOE and TMEM106B, respectively. F, G Distribution...
GOETHE UNIVERSITY FRANKFURT IMAGE: BONE MARROW SMEAR FROM A CHILD WITH DOWN SYNDROME WHO SUFFERS FROM LEUKEMIA. THE PURPLE-COLOURED LEUKEMIC BLASTS DISPLACE NORMAL BLOOD FORMATION. CREDIT: JAN KLUSMANN, UNIVERSITY HOSPITAL FRANKFURT FRANKFURT. Leukaemia (blood cancer) is a group of malignant and aggressive diseases of the blood-forming cells in the bone marrow. Very intensive chemotherapy and...
