by Florida Atlantic University Credit: Pixabay/CC0 Public Domain The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1. Whether this skewed...
by Jane Langille, Cornell University Credit: Pixabay/CC0 Public Domain Weill Cornell Medicine investigators have identified definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC). Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients...
by Aarhus University Graphical abstract. Credit: Cell Reports Medicine (2022). DOI: 10.1016/j.xcrm.2022.100740 For decades, researchers from all over the world have been working hard to understand Alzheimer’s disease. Now, a collaboration between the Department of Biomedicine and the Department of Clinical Medicine at Aarhus University has resulted in a flock of minipigs that could lead to a...
September 22, 2022 – By Nina Bai “I think receiving this Breakthrough Prize is incredible, and I also definitely have the reward of seeing my patients completely changed by these new drugs,” said Emmanuel Mignot. “It’s a fantastic kind of human adventure.”Stanford Medicine photo Emmanuel Mignot, MD, PhD, the Craig Reynolds Professor of Sleep Medicine, is...
UNIVERSITY OF COLOGNE IMAGE: REPRESENTATIVE IMAGES OF NEURONAL ROSETTES DERIVED FROM CONTROL SAMPLES AND CAPRIN1+/- CELLS. CAPRIN1 PROTEIN (MAGENTA) COULD BE EASILY DETECTED IN THESE STRUCTURES. CREDIT: BRUNHILDE WIRTH, UNIVERSITY OF COLOGNE Two studies have revealed that certain disorders of the CAPRIN1 gene have significant consequences for people. First, the research team showed that insufficient...
by Jim Lynch, University of Michigan Abhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineering work on ovarian cancer cell research in the bio-engineering lab at the North Campus Research Center (NCRC). Credit: Marcin Szczepanski, Michigan Engineering The way that tumor cells enable...
by University of Southern California Credit: Pixabay/CC0 Public Domain A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer’s disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study. The protein, called SHMOOSE,...
by Rockefeller University Credit: Unsplash/CC0 Public Domain It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others. A new paper published in Nature may explain the genetic underpinnings of this dichotomy. The researchers demonstrated that mice with gene variants...
by Nina Grötschl, University of Veterinary Medicine—Vienna Credit: Pixabay/CC0 Public Domain The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team led by scientists from Vienna now showed that EVI1’s cancer causing effect relies on activating a single gene—the stem cell transcription factor ERG. The...
by Delthia Ricks , Medical Xpress Credit: Unsplash/CC0 Public Domain Just as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to chemotherapy. And among tumors, those associated with triple negative breast cancer and ovarian tumors can develop a powerful form of resistance. In an intriguing line of research,...
