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Gene variant may underlie diabetes disparities: study
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Gene variant may underlie diabetes disparities: study

NEWS RELEASE 25-JUN-2024 Peer-Reviewed Publication VANDERBILT UNIVERSITY MEDICAL CENTER IMAGE: CO-CORRESPONDING AUTHOR AYUSH GIRI, PHD. CREDIT: VANDERBILT UNIVERSITY MEDICAL CENTER A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine. The...

New gene linked to osteoporosis identified
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New gene linked to osteoporosis identified

JULY 1, 2024 by Osaka University Molecular mechanism of senescence induced by osteoblast MEN1 deficiency SASP: senescence-associated secretory phenotype. Credit: Aging Cell (2024). DOI: 10.1111/acel.14254Osteoporosis—weakening of the bones with age—affects millions worldwide, and this figure is increasing annually as the global population ages. It is associated with the aging, or “senescence,” of bone cells, but...

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Pancreatic Gene Therapy: A ‘One-and-Done’ GLP-1 Treatment?

MEDBRIEF Nancy A. Melville June 25, 2024 TOPLINE:An experimental pancreatic gene therapy given to a mouse model of obesity as a one-time, single-dose treatment showed improvements in body composition and fasting glucose comparable with those achieved with the glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide, without the reversal of fat-loss and glycemia improvements that are...

Study elucidates crucial role of G900 gene enhancers in asthma-associated inflammation
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Study elucidates crucial role of G900 gene enhancers in asthma-associated inflammation

JUNE 24, 2024 by Chiba University Researchers identify G900-dependent mechanism of in vivo Th2 differentiation. Credit: Arifumi Iwata from Chiba UniversityAsthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper...

Oral Contraceptive Use Linked to Hair Loss
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Oral Contraceptive Use Linked to Hair Loss

The contraceptive pill could increase the risk of frontal fibrosing alopecia if a mutation in a specific gene is present.NewsPublished: May 30, 2024 | Original story from King’s College London Credit: Reproductive Health Supplies Coalition / Unsplash. A new study published in JAMA Dermatology looks at how taking the oral contraceptive pill could be linked...

Team finds new potential causes of rare and lethal bone cancer
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Team finds new potential causes of rare and lethal bone cancer

MAY 31, 2024 by Children’s Hospital Los Angeles Credit: Molecular Cancer Research (2024). DOI: 10.1158/1541-7786.MCR-23-0741 Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and 5% of these are in children. These tumors can...

Researchers identify a genetic cause of intellectual disability affecting tens of thousands
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Researchers identify a genetic cause of intellectual disability affecting tens of thousands

MAY 31, 2024 by The Mount Sinai Hospital Schematic showing the structures of U4 and U6 RNAs, and the interactions between them. Mutations in the highlighted regions of U4 cause a neurodevelopmental disorder that affects tens of thousands. Credit: Lab of Ernest Turro, Ph.D., at Icahn Mount Sinai. Researchers at the Icahn School of Medicine...

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LJI scientists develop new method to match genes to their molecular ‘switches

New research may help scientists hunt down solid tumors and better diagnose disease Peer-Reviewed PublicationLA JOLLA INSTITUTE FOR IMMUNOLOGY THE NEW RESEARCH WAS LED BY LJI PROFESSOR ANJANA RAO, PH.D., (LEFT) AND LJI ASSOCIATE PROFESSOR FERHAT AY, PH.D. LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for...

Gene editing breakthrough could soon cure herpes for good
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Gene editing breakthrough could soon cure herpes for good

(© DOC RABE Media – stock.adobe.com)HEALTH & MEDICAL NEWS by Chris Melore MAY 14, 2024 SEATTLE — A revolutionary new treatment may forever get rid of the painful and embarrassing blisters that come from a herpes flare-up. The herpes viruses that cause either cold sores around the mouth or blisters near the genitals stick around...