MAY 16, 2024 by Netherlands Cancer Institute Organoid of a patient with colon cancer, treated (right) and not treated with the chemotherapy etoposide. The treatment causes DNA damage and a reduction in protein synthesis. This triggers a stress signal that causes the cells to die. Orange: marker for DNA damage. Green: marker for protein synthesis....
Category: <span>Genetics</span>
Important Gene in the Fight Against Prostate Cancer Identified
Men with mutations in a particular gene are at greater risk of developing metastases after prostate cancer.News Published: May 17, 2024 | Original story from Aarhus University Credit: iStock. Finding out that cancer has spread is always unwelcome news. A study from Aarhus University has identified a gene that determines whether patients with prostate cancer...
New mechanisms underlying tumor variety in brain cancers discovered
MAY 20, 2024 by Melissa Rohman, Northwestern University High-grade meningiomas are distinguished by regionally distinct intratumor immune infiltration, MAPK signaling, PI3K-AKT signaling, and cell proliferation. Credit: Amy B. Heimberger, MD, Ph.D. Investigators have discovered new mechanisms underlying the diversity of characteristics within a single tumor, as well as treatment resistance, in the most common type...
Hungry gut’ gene test shows who will benefit most from Wegovy – genetics
by Robin Foster You’ve watched others shed pounds in a matter of weeks after taking one of the new blockbuster weight-loss drugs, so you decide to try one of the medications yourself, only to discover the needle on your bathroom scale barely budges. Why? New research presented Monday at the Digestive Disease Week conference in...
Researchers identify mutation that alters Alzheimer’s disease progression
by University of Malaga Researchers identify a mutation that alters Alzheimer’s disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 different entities. Credit: University of MalagaThe scientist of the Faculty of Medicine of the University of Malaga José Luis Royo has coordinated a study that summarizes eight years of...
Blood mutations increase risk for acute kidney injury, says study
by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized...
Researchers Uncover How Gene Traits Are Passed On
Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases. the University of Hong Kong Credit: iStock. A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong (HKU) collaborating with Professor Ning GAO and Professor Qing LI from Peking University...
Genetic “Switch” Controlling Anxiety Discovered
A genetic “switch” has been identified that plays a role in controlling anxiety levels, which could provide a new anxiety drug target. University of Aberdeen Credit: Liza Summer/ Pexels New research from the University of Aberdeen has identified an area of DNA in the human genome that plays a role in controlling anxiety. In the...
Unusual Gene Structure Shields Common Gut Bacterium Against Antibiotic
A newly discovered genetic arrangement may help a common bacterium in the human gut protect itself from a widely used antibiotic. Original story from The Marine Biological Laboratory Credit: Don Stalons/ CDC Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel...
Blood mutations increase risk for acute kidney injury, says study
by Vanderbilt University Medical Center Tet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit: Nature Medicine (2024). DOI: 10.1038/s41591-024-02854-6A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults...