September 12, 2024 by Institute for Research in Biomedicine (IRB Barcelona) Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients’ response to checkpoint inhibitors (CPIs). The study, which has been published in Nature Genetics, validates these factors in more than 1,400 patients and diverse types...
September 12, 2024 by Max Delbrück Center for Molecular Medicine Images of the colons of conventional (left) and germ free (right) mice showing how bacterial colonization affects the distribution of immune cells along the mouse intestine. CD45 immune cells are show in red, CD3 immune cells are shown in yellow. Immune cells are concentrated close...
News Release 11-Sep-2024 Researchers from Monash University and Osaka University examine the benefits of using regulatory T cells as a universal regenerative medicine approach Peer-Reviewed PublicationImmunology Frontier Research Center (IFReC) – Osaka University Osaka, Japan – Investigators are constantly aiming to identify new therapeutic approaches for regenerative medicine. Recent strategies have focused on harnessing the...
September 9, 2024 by Katherine Fenz, Rockefeller University Glycosphingolipids (in pink, via Cholera Toxin B) are so critical for cancer immune evasion that certain cancer cells cannot proliferate without it. Credit: Rockefeller UniversityCancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags...
September 5, 2024 by Pasteur Institute Credit: CC0 Public DomainA total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term remission of HIV infection after receiving a bone marrow transplant to treat...
September 5, 2024 by Frederike Buhse, Exzellenzcluster Präzisionsmedizin für chronische Entzündungserkrankungen Graphical abstract. Credit: Immunity (2024). DOI: 10.1016/j.immuni.2024.08.005In autoimmune diseases, the immune system mistakenly attacks the body’s own structures. A research team from Kiel, Lübeck and Berlin has now succeeded in analyzing certain pathogenic immune cells more precisely using a method they developed. They discovered...
September 5, 2024 by The Mount Sinai Hospital Credit: Science (2024). DOI: 10.1126/science.adn0327A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth,...
September 4, 2024 by Mass General Brigham T cells promote allergic itch through a secreted factor. Credit: Nature (2024). DOI: 10.1038/s41586-024-07869-0Why do some people feel itchy after a mosquito bite or exposure to an allergen like dust or pollen, while others do not? A new study has pinpointed the reason for these differences, finding the...
September 4, 2024 by Cedars-Sinai Medical Center An aberrant immune–epithelial progenitor niche is a hallmark of post-viral lung disease. Credit: Nature (2024). DOI: 10.1038/s41586-024-07926-8Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs’ protective barrier from healing after viral infections like COVID-19. The findings, published in...
News Release 4-Sep-2024 Researchers explore how hypernatremia affects microglial responses and evaluate potential therapeutic options for managing these effects Peer-Reviewed PublicationFujita Health University Microglial Response to Hypernatremiaimage: A study by researchers from Fujita University reveals that hypernatremia enhances NFAT5 and NO production in microglia and minocycline mitigates this response. The image above is a schematic...
