September 3, 2024 by Johns Hopkins University School of Medicine In a sea of cancer cells (blue), macrophages (green) are close neighbors to metastatic-initiating cancer cells (magenta). Credit: Won Jin Ho, Johns Hopkins Kimmel Cancer CenterIn a study using human breast cancer cells, scientists say they have potentially identified immune system white blood cells that...
September 3, 2024 by University of Texas at Austin Graphical abstract. Credit: Cell Reports Medicine (2024). DOI: 10.1016/j.xcrm.2024.101668Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly related SARS-like coronaviruses that infect other animals. As part of a new study on hybrid immunity...
August 30, 2024by Higher Education Press Credit: Tingting Wu, Lulu Wang, Chen Jian, Zhenhe Zhang, Ruiyin Zeng, Bobin Mi, Guohui Liu, Yu Zhang, Chen ShiA study in Frontiers of Medicine uncovers a unique reparative function of regulatory T cells (Tregs) in the process of fracture healing, a discovery that adds a new dimension to our...
August 30, 2024 by University of Tsukuba Graphical abstract. Credit: Clinical Immunology (2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in regulatory T (Treg) cells, which typically suppress immune responses, does not adequately control elderly-onset rheumatoid arthritis. In the arthritic environment, Treg cells exhibit altered metabolic activity, reduced suppressive function, and increased...
August 30, 2024 by JooHyeon Heo, Ulsan National Institute of Science and Technology Schematic image, showing the blockade of the endocytic pathway by UNI418 in SARS-CoV-2-infected cells. Credit: Experimental & Molecular Medicine (2024). DOI: 10.1038/s12276-024-01283-2In light of the ongoing threat posed by new viruses following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),...
SCIENCE & TECHNOLOGY NEWS Researchers from The University of Queensland have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness. Bacteria – illustrative photo. Image credit: Pixabay (Free Pixabay license) The research, led by Professor Ulrike Kappler from UQ’s School of Chemical and Molecular...
August 13, 2024 by Valerie Goodwin, University of Michigan Metabolic parameters in neutrophils from people in the control group, patients with APS, patients with aPL-only, and patients with Thromb (aPL–). Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI169893Neutrophils are an important type of white blood cell that help your immune system fight infections. One of...
August 6, 2024 by Marta Wegorzewska, Washington University School of Medicine Immunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body’s healthy cells inadvertently...
August 5, 2024 by Julie Grisham, Memorial Sloan Kettering Cancer Center Credit: CC0 Public DomainThe U.S. Food and Drug Administration (FDA) has granted accelerated approval for the immunotherapy afamitresgene autoleuecel (Tecelra, also known as afami-cel) for the treatment of adults with a rare soft tissue cancer called synovial sarcoma. Afami-cel is the first engineered T...
August 13, 2024 by CU Anschutz Medical Campus Acutal results of clinical trial participant with alopecia areata after four months of treament. Credit: Linda Crnic Institute for Down Syndrome Multi-organ autoimmunity and widespread autoantibody production in Down syndrome.A new study published in eLife by researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute)...
