News Release 12-Aug-2024 Macrophages exposed to low levels of ‘eat me’ antibodies consume more later Peer-Reviewed PublicationUniversity of California – Santa Barbara (Santa Barbara, Calif.) — The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white...
Category: <span>Immunology</span>
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Light-activated macrophages show increased appetite for cancer cells
August 12, 2024 by University of California – Santa Barbara Credit: Pixabay/CC0 Public DomainThe body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among these forces is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and cancer....
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Tpex cells: A game-changer in targeted tumor immunotherapy
August 8, 2024 by China Anti-Cancer Association the game-changer in targeted tumor immunotherapyTumor immunotherapy targeting Tpex. Credit: Cancer Biology & Medicine Progenitor exhausted CD8+ T (Tpex) cells have emerged as a pivotal component in tumor immunotherapy due to their unique ability to self-renew and rapidly proliferate. These cells have shown promise in expanding and differentiating...
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How the stressed-out brain can weaken the immune system
08 August 2024 Stress leads to disarray of the gut microbiome, which in turn causes inflammation and a drop in the body’s ability to fend off infection. By Sara Reardon The vagus nerve connects the brain region called the amygdala (red; artist’s illustration) to nerves for the Brunner’s glands in the gut.Credit: Sebastian Kaulitzki/Science Photo...
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Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma
July 26, 2024 by Impact Journals LLC Tumor infiltrating immune cell profiling according to high (cyan) and low (salmon) CD74:MIF levels (A) and CD74:DDT levels (B) using TIMER2.0 deconvolution analysis. Credit: 2024 Valdez et al.A new research paper was published in Oncotarget entitled, “Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.” Macrophage...
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Surprising finding in glioblastomas: Nearby bone marrow niches may serve as anti-tumor defense bases
July 31, 2024 by German Cancer Research Center Skull bone (gray) of a patient with glioblastoma. Vessels (red) in the inner cavities of the local bone marrow; the immune cells, which are only found enriched in the immediate vicinity of the tumor, are shown in green. Credit: Dobersalske/Scheffler / DKTKGlioblastomas are highly aggressive, usually incurable...
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Researchers warn of allergy risks from insect-based foods
July 31, 2024 by James Cook University Credit: Nathan MateusJames Cook University researchers say food derived from crickets and flies can cause allergic reactions in people with existing shellfish allergy—and this is not consistently picked up by currently available testing methods. Their study is published in Molecular Nutrition & Food Research. Professor Andreas Lopata and...
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Immune cell injections could prevent ischemic leg amputation
July 30, 2024 by King’s College London Credit: Pixabay/CC0 Public DomainA study has found that a subset of a special type of white blood cells called monocytes could be the key to regrowing blood vessels in the legs of patients with chronic limb-threatening limb ischemia (CLTI). Over the course of a seven-year study, the researchers...
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Recent study reveals key immune cells as critical factors in lung cancer prognosis
July 30, 2024 by Terasaki Institute for Biomedical Innovation Tissue-resident memory T cells impact non-small cell lung cancer immune microenvironment and prognosis. A machine learning model reveals the difference in the cancer subtypes. Credit: Terasaki InstituteAn extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of...
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NEW EVIDENCE SHEDS LIGHT ON ONE OF LONG COVID’S DRIVERS
JULY 29TH, 2024POSTED BY YALE(Credit: Getty Images) TAGS COVID-19IMMUNE SYSTEMSUNIVERSITY YALE UNIVERSITY New research offers evidence that autoimmunity—in which the body’s immune system targets its own tissues—is a driver in some cases of Long COVID. Why COVID-19 sometimes leads to Long COVID still confounds doctors, but researchers have several hypotheses to explain its often-debilitating symptoms....