JULY 2, 2024 by Cell Press Acute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public Domain Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies to treat cancer, auto-immune...
by RIKEN A newly developed method called ReapTEC allowed the discovery of thouands of active bidirectional enhancers. Further anaylis of GWAS data revelaed that various immune-mediated diseases, like multipkle sclerosis and rheumatoisd arthritis, are related to genetic variations within these enhancers. Credit: RIKEN Researchers led by Yasuhiro Murakawa at the RIKEN Center for Integrative Medical...
by Pohang University of Science and Technology Schematic of the mechanism of action of ETV5 on TFH cell differentiation. Credit: POSTECHA research team including Professor Yoontae Lee and Jiho Park, a Ph.D. candidate, from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) has discovered that a particular protein promotes the...
by Liz Ahlberg Touchstone, University of Illinois at Urbana-Champaign The team uses an inverted fluorescence microscope to image cancer cells that are targeted using different light spectra to initiate inflammatory cell death. The process could help create immunotherapy techniques for disease intervention. Credit: Fred Zwicky, University of Illinois at Urbana-ChampaignA new method of precisely targeting...
by Wiley Credit: Unsplash/CC0 Public Domain Based on focus groups with children and young people with peanut allergy, experts have published guidance for clinicians working in the UK’s National Health Service (NHS) to help them safely and equitably implement Palforzia peanut oral immunotherapy. Their recommendations are published in Clinical & Experimental Allergy. In 2022, the...
by Robin Foster In new vaccination guidance issued Wednesday, U.S. health officials now recommend that all Americans aged 75 and older get an RSV vaccine before fall arrives. However, those a bit younger—ages 60 to 74—should only seek the shot if they are vulnerable to severe RSV because of chronic medical conditions such as lung...
by University of California, San Francisco Credit: CC0 Public DomainHeadache, chills, tiredness may be evidence of a supercharged defense, according to UCSF-led study. Fewer than 1 in 4 people in the United States have received last year’s updated COVID-19 vaccine, despite a death toll of more than 23,000 Americans this year. One of the most...
JUNE 12, 2024 by Frontiers Credit: Pixabay/CC0 Public DomainThere are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa. In Europe, Latrodectus tredecimguttatus—the European black widow—inhabits the Mediterranean region, but recently and due to the...
NEWS RELEASE 12-JUN-2024 Subcutaneous biodegradable scaffolds for restimulating the antitumor activity of preadministered CAR-T cells Peer-Reviewed PublicationWYSS INSTITUTE FOR BIOLOGICALLY INSPIRED ENGINEERING AT HARVARD IMAGE: T-CELL ENHANCING SCAFFOLDS CAN BE LOCALLY INJECTED UNDER THE SKIN FOLLOWING CAR-T CELL THERAPY, AND ALLOWCIRCULATING CAR-T CELLS TO INFILTRATE THEIR 3-DIMENSIONAL POROUS SCAFFOLD STRUCTURE. THERE, CAR-T CELLS BECOME ACTIVATED...
MAY 31, 2024 by University of Texas M. D. Anderson Cancer Center Credit: Unsplash/CC0 Public Domain Researchers from The University of Texas MD Anderson Cancer Center presented positive clinical results from two studies today at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. The findings highlight strong remission and response rates and offer...
