Category: <span>Immunology</span>

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Antibody discovery promises new hope in influenza B battle, paves way for universal vaccine
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Antibody discovery promises new hope in influenza B battle, paves way for universal vaccine

JUNE 1, 2024 by Bill Snyder, Vanderbilt University Medical Center A 3D rendering shows one of the isolated antibodies, FluB-393, (blue) binding to the neuraminidase surface glycoprotein (red) of the influenza type B virus to prevent infection. Credit: Elad Binshtein, Ph.D., and Anthony CzelusniakResearchers at Vanderbilt University Medical Center have isolated human monoclonal antibodies against...

Q&A: Researchers determine that a subclass of stem cells replenish platelets more rapidly
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Q&A: Researchers determine that a subclass of stem cells replenish platelets more rapidly

JUNE 3, 2024 by Karolinska Institutet a, Left, experimental design (partly created with Biorender.com) for single-cell RNA sequencing of HSPCs generated by single Vwf-tdTomato+ P-HSCs (n = 7) or Vwf-tdTomato− multi-HSCs. Right, mean (dots indicate individual mice) contribution to blood lineages. b, UMAP of LIN−cKIT+ cells replenished by single Vwf-tdTomato+ P-HSCs (blue; n = 7 mice, 2,290 cells) or...

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Molecule produced in gut can have protective effect against flu, study shows

Molecule produced in gut can have protective effect against flu, study showsIn experiments with mice, researchers at the State University of Campinas in Brazil and the Pasteur Institute in Lille (France) found that viral load and inflammation decreased in animals infected by influenza virus when they were given the substance. Peer-Reviewed PublicationFUNDAÇÃO DE AMPARO À...

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New mRNA Vaccines in Development for Cancer and Infections

Medscape Medical News Klaus Fleck, MD May 02, 2024 BERLIN — To date, mRNA vaccines have had their largest global presence in combating the COVID-19 pandemic. Intensive research is underway on many other potential applications for this vaccine technology, which suggests a promising future. Martina Prelog, MD, a pediatric and adolescent medicine specialist at the...

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Research explains new method to engineer immune cells that could treat multiple cancer patients

by Linda Wang, University of California, Los Angeles A microscopy image shows an enhanced natural killer T cell (blue) attacking a human multiple myeloma cell (magenta). Credit: Lili Yang lab/UCLAImmunotherapies have revolutionized cancer treatment by harnessing the body’s own immune system to attack cancer cells and halt tumor growth. However, these therapies often need to...

B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptoms
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B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptoms

NEWS RELEASE 16-MAY-2024 B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptomsAbnormally active B cell metabolism causes an inflammatory immune response in individuals with MS, Penn Medicine research finds Peer-Reviewed PublicationUNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE IMMUNE CELL INTERACTIONS DRIVING MS ATTACKS. CREDIT: PENN MEDICINE PHILADELPHIA –...

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HIV Vaccine Candidate Induces Broadly Neutralizing Antibodies in Humans – immunology

A trial HIV vaccine has triggered broadly neutralizing antibodies in humans after just two immunizations.News Published: May 20, 2024 | Blake Forman Read time: 3 minutes Infection with HIV is currently manageable with lifelong antiretroviral medications, but neither a vaccine nor a cure is available. A critical roadblock in preventative vaccine development has been the...

Research finds the protein VISTA directly blocks T cells from functioning in immunotherapy
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Research finds the protein VISTA directly blocks T cells from functioning in immunotherapy

by Cleveland Clinic MAY 17, 2024 Credit: Pixabay/CC0 Public Domain A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment. The study, published in Science Immunology, explains that VISTA can bind to a protein called LRIG1 in T...

Immunotherapy Could Be Used To Boost the Immune System of Older Individuals
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Immunotherapy Could Be Used To Boost the Immune System of Older Individuals

Immunotherapy could be used to enhance immune responses in older people, making them less vulnerable to infections. News Published: May 16, 2024 | Original story from the University of Minnesota Credit: Congerdesign/ Pixabay Published in Nature Aging, University of Minnesota Medical School researchers provided new insight into enhancing immune responses in older individuals and the...

Novel mechanism supports antitumor response and T-cell survival
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Novel mechanism supports antitumor response and T-cell survival

by Melissa Rohman, Northwestern University Representative composite image of a breast cancer specimen stained by multi-color IHC comprising CD8, Ki67, GCLC, GPX4, 923 A2AR, PanCK and DAPI. Representative CD8+GPX4+ (blue arrow), CD8+GCLC+ (blue arrowhead), CD8+GPX4+GCLC+ 924 (red arrow), and CD8+Ki67+ GPX4+GCLC+ (red arrowhead) cells. Credit: Bin Zhang, PhDA recent Northwestern Medicine study has discovered a...