A single injection may have prevented the progression of the human immunodeficiency virus, or HIV, to up to four months, a new study suggests. Researchers in Taiwan reported that the antibodycalled UB-421 was safe and it effectively prevented the virus from destroying the immune system. They reported that a single injection of the antibody is as effective as a daily pill regimen. They published the results of...
Category: <span>Immunotherapy</span>
Post
Topical Immunotherapy keeps skin cancer risk at bay
Treating precancerous skin lesions prevents full-blown cancer WASHINGTON UNIVERSITY SCHOOL OF MEDICINE A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin. The study, from Washington University School of Medicine in St. Louis, Massachusetts General Hospital, and...
Post
Why some brain tumors respond to immunotherapy
NEW YORK, NY (February 15, 2019)– Columbia researchers have learned why some glioblastomas–the most common type of brain cancer–respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly effective treatments. The study, led by Raul Rabadan, PhD,...
Post
CAR-T immunotherapies may have a new player
Emerging CAR-T immunotherapies leverage modified versions of patient’s T-cells to target and kill cancer cells. In a new study, published June 28 online in Cell Stem Cell, researchers at University of California San Diego School of Medicine and University of Minnesota report that similarly modified natural killer (NK) cells derived from human induced pluripotent stem cells (iPSCs) also...
Post
UM researcher finds link between crystal methamphetamine and immune changes in HIV
UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants, such as methamphetamine, can negatively affect the health of HIV-positive persons even when they are adhering to medical treatment. IMAGE: ADAM CARRICO, PH.D., ASSOCIATE PROFESSOR OF PUBLIC HEALTH SCIENCES AND PSYCHOLOGY...
Post
Researchers identify a new way to promote tissue regeneration
Cell (stock image). The use of iPSCs to generate tissues would revolutionize transplantation, facilitating the growth of artificial organs, say authors. Houston Methodist researchers have identified an immune pathway that promotes the formation of a cell that can develop into new tissues and organs. In a new study published in the journal Stem Cells, a team...
Post
Pitt study provides clues to relationship between schizophrenia and rheumatoid arthritis
PITTSBURGH, Feb. 24, 2017 – An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a...
Post
Absent tumor-suppressors allow melanoma to thwart immunotherapy
Researchers identified a set of genetic changes that predict whether melanoma patients will respond to checkpoint inhibitor therapies. It’s what’s missing in the tumor genome, not what’s mutated, that thwarts treatment of metastatic melanoma with immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in Science Translational Medicine. Whole...
Post
Two babies with terminal cancer CURED after 'miracle' treatment
Two British infants, 11 and 16 months old, have been cured of leukemia Both have been in remission for at least a year post-treatment London doctors used genetically engineered immune cells to treat the cancer This could lead to off-the-shelf cellular therapy at a low cost for future patients Two babies who were...
Post
The immunotherapy, pembrolizumab, is active against mucosal melanoma tumors
And prolongs survival for patients with bladder cancer Amsterdam, The Netherlands: Clinical trials of a new immunotherapy, pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma. The findings were presented in two presentations at the European Cancer Congress 2017...