Chronic rhinosinusitis is distinct from your average case of seasonal allergies. It causes the sinuses to become inflamed and swollen for months to years at a time, leading to difficulty breathing and other symptoms that make patients feel miserable. In some people, this condition also produces tissue outgrowths known as nasal polyps, which, when severe...
Category: <span>Inflammation</span>
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New biomarkers of inflammation identified as risk of polyneuropathy
DEUTSCHES ZENTRUM FUER DIABETESFORSCHUNG DZD Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes. First symptoms are often pins-and-needles sensations in the feet. Although polyneuropathy is present in about 30% of people with diabetes, it often...
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Double discovery reveals insights behind brain degeneration
Research discoveries revealing the genetic causes of neurological degeneration could be a key to slowing the progression of devastating diseases. A research team led by Dr Marija Kojic and Professor Brandon Wainwright from The University of Queensland’s Institute for Molecular Bioscience (IMB) and Dr Sebastian Glatt from the Jagiellonian University in Krakow, made the findings...
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The roles of RNA-RNA interactions
July 20, 2018, Ludwig Maximilian University of Munich Chronic regeneration of damaged endothelial cells at sites of disturbed blood flow in the vasculature promotes the development of atherosclerosis. Now an LMU team has further elucidated the role of a short RNA molecule in atherogenesis. Credit: Design-Cells / fotolia.com Atherosclerosis – the condition is popularly known as hardening...
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Study identifies a link between antidepressant treatment resistance and inflammation
Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. Levels of inflammation can be easily measured by simple blood tests, like C-reactive protein (CRP), readily available in clinics and hospitals throughout the U.S. Credit: Emory University...
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Potent new mechanism of action for treatment of inflammatory bowel disease revealed
Through research on the small molecule analogue of E6007 which is under clinical development as a treatment for inflammatory bowel disease, a novel mechanism of action was revealed in which this analogue inhibited the adhesion and infiltration of various leukocytes through the blockade of the interaction between calreticulin and the leukocyte adhesion molecule integrin α by associating...