Researchers at the University of Bonn determine how dangerous inflammations in the brain are caused UNIVERSITY OF BONN The so-called CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of “sensor” with which neurons measure and control the activity of certain immune cells in the brain....
Category: <span>Inflammation</span>
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Gum disease treatment may improve symptoms in cirrhosis patients
Study finds routine oral care alters gut bacteria and reduces inflammation and cognitive problems AMERICAN PHYSIOLOGICAL SOCIETY Rockville, Md. (August 29, 2018)–Routine oral care to treat gum disease (periodontitis) may play a role in reducing inflammation and toxins in the blood (endotoxemia) and improving cognitive function in people with liver cirrhosis. The study is published...
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New target could prevent progression of liver damage to cancer
AUGUSTA, Ga. (Aug. 27, 2018) – Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report. The relentless, increased activity of TREM-1 in turn accelerates injury and scarring of the liver, a first step toward cirrhosis and liver cancer,...
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New research reveals how the body clock controls inflammation
Researchers at RCSI and Trinity College Dublin have revealed insights into how the body clock controls the inflammatory response, which may open up new therapeutic options to treat excess inflammation in conditions such as asthma, arthritis and cardiovascular disease. By understanding how the body clock controls the inflammatory response, we may be able to target these...
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Cellular changes lead to chronic allergic inflammation in the sinus
Chronic rhinosinusitis is distinct from your average case of seasonal allergies. It causes the sinuses to become inflamed and swollen for months to years at a time, leading to difficulty breathing and other symptoms that make patients feel miserable. In some people, this condition also produces tissue outgrowths known as nasal polyps, which, when severe...
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New biomarkers of inflammation identified as risk of polyneuropathy
DEUTSCHES ZENTRUM FUER DIABETESFORSCHUNG DZD Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes. First symptoms are often pins-and-needles sensations in the feet. Although polyneuropathy is present in about 30% of people with diabetes, it often...
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Double discovery reveals insights behind brain degeneration
Research discoveries revealing the genetic causes of neurological degeneration could be a key to slowing the progression of devastating diseases. A research team led by Dr Marija Kojic and Professor Brandon Wainwright from The University of Queensland’s Institute for Molecular Bioscience (IMB) and Dr Sebastian Glatt from the Jagiellonian University in Krakow, made the findings...
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The roles of RNA-RNA interactions
July 20, 2018, Ludwig Maximilian University of Munich Chronic regeneration of damaged endothelial cells at sites of disturbed blood flow in the vasculature promotes the development of atherosclerosis. Now an LMU team has further elucidated the role of a short RNA molecule in atherogenesis. Credit: Design-Cells / fotolia.com Atherosclerosis – the condition is popularly known as hardening...
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Study identifies a link between antidepressant treatment resistance and inflammation
Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. Levels of inflammation can be easily measured by simple blood tests, like C-reactive protein (CRP), readily available in clinics and hospitals throughout the U.S. Credit: Emory University...
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Potent new mechanism of action for treatment of inflammatory bowel disease revealed
Through research on the small molecule analogue of E6007 which is under clinical development as a treatment for inflammatory bowel disease, a novel mechanism of action was revealed in which this analogue inhibited the adhesion and infiltration of various leukocytes through the blockade of the interaction between calreticulin and the leukocyte adhesion molecule integrin α by associating...