by Universität Leipzig Philipp Rabe and Aenne-Dorothea Liebing, both study authors, working with cell cultures. Credit: Dr. Claudia Stäubert Cancer cells show unchecked rapid growth beyond tissue boundaries that is no longer stopped by normal control mechanisms. Due to this rapid growth, the metabolism of cancer cells is altered compared to that of cells that...
Category: <span>Metabolic</span>
Uncovered: Key to how exercise protects against consequences of ageing
by Monash University Staining showing mitochondria within individual muscle fibres. Credit: Monash University Monash University, Australia scientists have discovered an enzyme that is key to why exercise improves our health. Importantly this discovery has opened up the possibility of drugs to promote this enzyme’s activity, protecting against the consequences of aging on metabolic health, including...
Experimental treatment prevents Alzheimer’s-associated weight gain in mice
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO Treatment with a bile acid derivative known as TUDCA (tauroursodeoxycholic acid) can mitigate metabolic abnormalities associated with Alzheimer’s disease, such as alterations in food intake and body weight, improving the patient’s quality of life, according to the findings of a study conducted at the University...
Researchers uncover potential way to protect against diet-induced obesity and inflammation
WORLDWIDE CANCER RESEARCH IMAGE: PROFESSOR RAUL MENDEZ CREDIT: WORLDWIDE CANCER RESEARCH Researchers in Spain, funded by the UK charity Worldwide Cancer Research, have discovered a new drug target that could help protect against diet-induced obesity and its related health issues. The research, led by Professors Mercedes Fernandez and Raul Mendez, found that a protein called...
Researchers uncover potential way to protect against diet-induced obesity and inflammation
IMAGE: PROFESSOR RAUL MENDEZ CREDIT: WORLDWIDE CANCER RESEARCH Researchers in Spain, funded by the UK charity Worldwide Cancer Research, have discovered a new drug target that could help protect against diet-induced obesity and its related health issues. The research, led by Professors Mercedes Fernandez and Raul Mendez, found that a protein called CPEB4 was present...
Low-frequency intermittent fasting prompts anti-inflammatory response
by Intermountain Healthcare Intermittent fasting may not only be a hot dieting trend, but it also has broader health benefits, including helping to fight inflammation, according to a new study from researchers at the Intermountain Healthcare Heart Institute in Salt Lake City. Credit: Intermountain Healthcare Intermittent fasting may not only be a hot dieting trend,...
Hemoglobin reflects metabolic health: High levels are linked to common public health problems
by University of Oulu Haemoglobin. Credit: University of Oulu / Juha Sarkkinen Hemoglobin is a protein found in the blood and a key oxygen transporter in the body. High hemoglobin levels have generally been considered desirable for a person’s health. However, the latest research evidence appears to point in the opposite direction: high hemoglobin levels...
Achieving inner balance: How to keep metabolites on the level
UNIVERSITY OF TSUKUBA Tsukuba, Japan – Keeping everything running smoothly inside the human body is a tricky business that involves a multitude of checks and balances to make sure that an exquisite equilibrium is maintained. Now, researchers from Japan have identified a single protein that helps balance both sugar and fat levels in the liver...
How glycogen is linked to heat generation in fat cells
by University of California – San Diego Artistic rendering of a brown fat cell with nucleus in pink, mitochondria in purple, and yellow lipid droplets scattered throughout. Credit: Scientific Animations Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers...
Genetic Variants Associated with Visceral Fat Accumulation Correlate with Longevity
It is well established that excess visceral fat is harmful. This tissue is metabolically active, and generates increased chronic inflammation through numerous mechanisms: a greater number of senescent cells; signaling by fat cells that appears similar to that produced by infected cells; increased debris from dead and dying fat cells that provokes the immune system....