by UT Southwestern Medical Center A UTSW study identified a type of blood vessel cell that triggers inflammation in fat tissue. Above, inflammatory immune cells (green) surround fat cells (red) in obesity and contribute to the development of metabolic disease. Credit: UT Southwestern Medical Center Dec. 30, 2020—When fat cells in the body are stuffed with...
Category: <span>Metabolic</span>
Hopes of new treatment strategies for glaucoma
by Karolinska Institute Credit: CC0 Public Domain In the search for new ways to treat the incurable eye disease glaucoma, researchers at Karolinska Institute and St. Erik Eye Hospital have discovered more clues as to its pathogenesis. A new study shows how metabolic disturbance of the neurons coincide with raised pressure in the eye. In animal...
Aging, diet-induced obesity, and metabolic disease link explored in new research
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON Unraveling the links among obesity, aging, telomere lengths and metabolic diseases is the subject of the study published today in Nature Metabolism by a collaborative research team at The University of Texas Health Science Center at Houston (UTHealth). Telomeres act as protective caps at the end of chromosomes to...
Water may be an effective treatment for metabolic syndrome
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS AURORA, Colo. (Dec. 15, 2020) – Researchers at the University of Colorado Anschutz Medical Campus have discovered that fructose stimulates the release of vasopressin, a hormone linked to obesity and diabetes. They also found that water can suppress the hormone and alleviate these conditions in mice. “The clinical significance of this...
Study suggests sugary diet endangers waste-eating protein crucial to cellular repair
by Tufts University Credit: Pixabay A protein that functions like the vintage video game Pac-Man, eating toxic cellular waste caused by high sugar intake, is itself compromised by a sugary diet, according to the results of a study in mice with potential implications for humans. The study, led by a research team at Tufts University joined by researchers at eight...
In liver, a stressed cell can be bad news for its neighbors
HARVARD T.H. CHAN SCHOOL OF PUBLIC HEALTH A key protein in the communication channels between cells can allow a stress response in one liver cell to spread to neighboring liver cells in mice, causing otherwise healthy cells to become dysfunctional, according to new research co-led by Harvard T.H. Chan School of Public Health and Sheba...
Researchers identify bacteria that promote metabolic and mental health
by University College Cork B. longum APC1472 increases Bifidobacterium abundance without impacting the overall composition of the gut microbiota in humans. The gut microbiota was assesed at the beginning (pre) and end of the study (12 weeks, past). Alpha (A-C) and beta diversity (D) were investigated, as wel as the bacterial genera present (E-F). Microbial taxa...
Brown fat: Implications in obesity
by Masonic Medical Research Institute The Lin Lab at the MMRI, quantified the number of brown fat cells present in newborn animals. For years, researchers have argued over whether brown fat continues to grow after birth. Dr. Lin and his team have become the first to prove that it does. Credit: Masonic Medical Research Institute Brown fat, also known as brown...
Study reveals connection between gut bacteria and vitamin D levels
by Heather Buschman, PhD, University of California – San Diego Credit: Unsplash/CC0 Public Domain Our gut microbiomes—the many bacteria, viruses and other microbes living in our digestive tracts—play important roles in our health and risk for disease in ways that are only beginning to be recognized. University of California San Diego researchers and collaborators recently demonstrated...
Study: gut hormones’ regulation of fat production abnormal in obesity, fatty liver disease
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, NEWS BUREAU CHAMPAIGN, Ill. — Gut hormones play an important role in regulating fat production in the body. One key hormone, released a few hours after eating, turns off fat production by regulating gene expression in the liver, but this regulation is abnormal in obesity, researchers at the University of...