CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) IMAGE: FROM LEFT TO RIGHT: REBECA ACÍN-PÉREZ, SALVADOR IBORRA, JOSÉ ANTONIO ENRÍQUEZ AND DAVID SANCHO. Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA — Penn Medicine researchers have solved a decades old mystery around a key molecule fueling the power plant of cells that could be exploited to find new ways to treat diseases, from neurodegenerative disorders to cancer. Reporting in a new study published today in Nature, researchers from the Department...
Patients in primary care clinic program lost 5 percent of body weight PENNINGTON BIOMEDICAL RESEARCH CENTER BATON ROUGE, Louisiana – Low-income Louisiana patients enrolled in a tailored obesity intervention program lost much more weight than counterparts receiving usual care. Study results were published this week in The New England Journal of Medicine. This population, who...
by Jackie Kruszewski, Virginia Commonwealth University A Virginia Commonwealth University researcher has published preliminary but striking evidence that shows the transplantation of gut bacteria may have implications for addiction disorders. Jasmohan Bajaj, M.D., a gastroenterologist and liver specialist, transplanted bacteria from another person’s stool into 10 volunteers with severe alcohol use disorder and cirrhosis. Nine...
Scientists at the University of Bonn identify previously unknown disease mechanism UNIVERSITY OF BONN DEOXYSPHINGOLIPIDS (GREEN) INTERFERE NOT ONLY WITH THE WORK OF THE MITOCHONDRIA (RED) BUT ALSO WITH CELL DIVISION. SOME OF THEM THEREFORE HAVE TWO NUCLEI (TURQUOISE). view more CREDIT: © AG KÜRSCHNER/UNIVERSITÄT BONN A congenital disorder of the fat metabolism can apparently...
by Joslin Diabetes Center Microscopic images of the various types of fat tissues developed in mice after transplantation. Top panels show the fat tissue’s general morphology, and the bottom panels are the tissue sections stained with hUCP1 (red color), which is unique for brown fat cells. These images show that while the HUMBLE fat cells...
by The Wistar Institute According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells. These messages are packaged into particles called extracellular vesicles (EVs) and reprogram mitochondrial shape and position within the recipient normal cells to ultimately promote deregulated...
Loss of a specific enzyme increases fat metabolism and exercise endurance in mice. Sugars and fats are the primary fuels that power every cell, tissue, and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells will switch to breaking down...
by Steve Lundeberg, Oregon State University A compound given as a dietary supplement to overweight but otherwise healthy people in a clinical trial caused many of the patients to slim down, research by Oregon State University and Oregon Health & Science University showed. The research, published in the Journal of Nutrition, analyzed the effects of...
The UPV/EHU-University of the Basque Country shows that maintaining osteopontin delays the onset of metabolic fatty liver disease during ageing UNIVERSITY OF THE BASQUE COUNTRY THE STUDY INDICATES THAT OSTEOPONTIN IS NECESSARY TO PREVENT THE EARLY ONSET OF NON-ALCOHOLIC FATTY LIVER DISEASE LINKED TO AGEING view more Metabolic fatty liver disease, known as non-alcoholic fatty...
