Category: <span>Metabolic</span>

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In Alzheimer Research, Glucose Metabolism Moves to Center Stage

Bridget M. Kuehn, MSJ JAMA. Published online January 8, 2020. doi:10.1001/jama.2019.20939 Areas or patterns of reduced glucose metabolism are often seen in brain scans of patients with Alzheimer disease and other dementias. Now, a growing body of evidence suggests that glucose hypometabolism may be more than just a biomarker on brain scans: it may be a key...

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Liposuction benefits women with lipedema

(HealthDay)—Liposuction improves the quality of life for women with lipedema, according to a study published in the December issue of Plastic and Reconstructive Surgery. Anna-Theresa Bauer, M.D., from Technical University Munich in Germany, and colleagues conducted an online survey of 209 female patients (average age, 38.5 years) with lipedema who had undergone tumescent liposuction to...

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Sleep-Disordered Breathing Tied to Accelerated Aging

Megan Brooks June 13, 2019 SAN ANTONIO — Sleep-disordered breathing (SDB), and the disruption in nightly sleep it causes, speeds up the aging process, according to preliminary research. SDB is a common disorder that results in oxidative stress and inflammation and is associated with several age-related health disorders. However, it hasn’t been well studied with...

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New insights into anti-obesity mechanisms of caffeine

By Rich Haridy Anecdotally, caffeine has long been considered an effective appetite-suppressant, and it has been shown to effectively speed up the body’s fat metabolism processes. Now, new research from the University of Illinois has homed in on another fascinating mechanism that may explain caffeine’s anti-obesity properties. The research initially focused on mate tea, a popular...

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GDF15 mediates the effects of metformin on body weight and energy balance

Anthony P. Coll, Michael Chen, Stephen O’Rahilly Nature (2019) , Cite this article, 53 Altmetric, Metrics details AbstractMetformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk1,2. Over 60% of this effect is attributable to the ability of metformin to lower body weight in a...

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Magnesium deprivation stops pathogen growth

IMAGE: THIS IS AN ELECTRON MICROSCOPE IMAGE OF A MACROPHAGE (BLUE) INFECTED WITH SALMONELLA (RED). CREDIT: UNIVERSITY OF BASEL, BIOZENTRUM When pathogens invade the cells, our body combats them using various methods. Researchers at the University of Basel’s Biozentrum have now been able to show how a cellular pump keeps such invading pathogens in check. As the researchers report...

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Anti-obesity effect of resveratrol and quercetin metabolites

by University of the Basque Country Resveratrol and quercetin are two functional ingredients to which a fat-reducing effect has been attributed in experiments conducted in vivo and in vitro. Yet their rapid metabolism means that only a tiny fraction of these compounds reach organs and tissue. Now, a new study suggests that their metabolism should...

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New finding offers possibility for preventing age-related metabolic disease

by Brita Belli, Yale University A study by researchers at Yale has uncovered why belly fat surrounding organs increases as people age, a finding that could offer new treatment possibilities for improving metabolic health, thereby reducing the likelihood for diseases like diabetes and atherosclerosis that stem from inflammation. Led by Dr. Vishwa Deep Dixit, the...

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Gastric Volume Reduction Surgery Leads to Blood Serum Proteome Changes

By Christian Zerfaß, Ph.D. Obesity is an increasingly common health problem. To counter obesity, gastric surgeries can be carried out to reduce the gastric volume, such as laparoscopic gastric plication (LGP). It is conceivable that a lower gastric volume leads to reduced food uptake, and thus caloric intake. However, wider metabolic changes can follow gastric...