Category: <span>Metabolic</span>

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Bariatric surgery is safe for teens with morbid obesity

New Penn Medicine study shows the risks of complications, readmissions may be lower than the risks associated with lifelong obesity UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA — Bariatric surgery is safe and, in many cases, beneficial for teenagers with morbid obesity who would otherwise face a heightened risk of developing severe health problems, including heart disease and stroke, according to a new...

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Fat accumulations in airways of obese people detected for first time

By Rich Haridy | October 20, 2019 A novel study has for the first time detected significant accumulations of fatty tissue in airway walls of obese and overweight people. The new research suggests these fat accumulations could explain why overweight individuals are at higher risk of respiratory disease and asthma. “Being overweight or obese has already been linked to having asthma or having worse asthma symptoms,” explains Peter Noble,...

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New metabolic discovery may inform heart disease, diabetes solutions

Posted Yesterday Science may be inching closer to thwarting obesity, heart disease and Type 2 diabetes, as Cornell biochemists have uncovered a key step in how the human body metabolizes sugar, according to new research published in the Journal of Biological Chemistry. Martha S. Field, assistant professor of nutritional sciences, has further characterized this human metabolic pathway, by identifying two enzymes called sorbitol dehydrogenase (SORD)...

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Researchers discover new, treatable pathway known to cause hypertension in obese people

by Brian H. Waters, Johns Hopkins University School of Medicine There’s no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure. Blocking one of these molecules—a signaling channel...

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Lack of sleep affects fat metabolism

by American Society for Biochemistry and Molecular Biology We’re all a little short on sleep during the work week. A new study adds to the mounting evidence about just how harmful lack of sleep can be. In the Journal of Lipid Research, researchers at Pennsylvania State University report that just a few days of sleep...

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Researchers develop new drug that fights cancer with less renal toxicity

by National University of Singapore A team of pharmacists and chemists from the National University of Singapore (NUS) has developed a new anti-cancer drug that has less toxic effects to the kidneys. The new drug works like a “magic bullet” that is delivered directly to the mitochondria—the power generators of cells—of cancer cells. Once the drug reaches the tumor, two active molecules—an anti-cancer drug and a sensitizer—are released at once,...

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Discovery of tanycytic TSPO inhibition as a potential therapeutic target for obesity treatment

by Nari Kim, Daegu Gyeongbuk Institute of Science and Technology (DGIST) Professor Eun-Kyoung Kim (director of Neurometabolomic Research Center) has discovered new targets to prevent and treat high-fat diet-induced obesity. This research achievement is expected to propose a new direction for developing obesity treatment. Due to westernized eating habits in today’s society, the prevalence of...