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Commensal T cells: How a healthy microbiome reduces gut inflammation
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Commensal T cells: How a healthy microbiome reduces gut inflammation

by Columbia University Irving Medical Center Graphical abstract. Credit: Immunity (2023). DOI: 10.1016/j.immuni.2023.11.003The microbiome has a profound influence on our health, but exactly how our resident bacteria wield their power is still unclear. A type of T cell appears to provide some answers for gastrointestinal health, a study of the mouse microbiome finds. The study, appearing...

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The surprisingly resourceful ways bacteria thrive in the human gut

Survey of bacterial genomes highlights the arsenal of enzymes microbes use to produce energy in the oxygen-poor environment of the gutPeer-Reviewed Publication UNIVERSITY OF CHICAGO The gut microbiome is so useful to human digestion and health that it is often called an extra digestive organ. This vast collection of bacteria and other microorganisms in the...

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Gut microbes revealed as key players in liver disease solutions

Chinese Academy of SciencesIn the editorial published on 4 September 2023, in the “gut-liver axis” special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota...

Could artificial sweeteners alter your microbiome?
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Could artificial sweeteners alter your microbiome?

by Dennis Thompson You may think that artificial sweeteners can help you lose some weight, but a new study finds they are no good for your gut’s microbiome. People who use aspartame (Equal), sucralose (Splenda), saccharin (Sweet’N Low), or stevia leaf extract tended to have intestinal bacteria colonies that differed significantly from those of people...

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Your unique microbiome may be used to improve and personalize your future medical experience

By Hugo Francisco de Souza Reviewed by Benedette Cuffari, M.Sc.In a recent study published in the journal Nature Reviews Microbiology, researchers summarize over 200 publications associating microbiomes with clinical diagnostic and precision therapeutic interventions. Study: Utilization of the microbiome in personalized medicine. Image Credit: FOTOGRIN / Shutterstock.com Gut microbiota and its potential in personalized medicineThe...

Gut microbes may determine patients’ response to a drug that delays onset of type 1 diabetes
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Gut microbes may determine patients’ response to a drug that delays onset of type 1 diabetes

by Delthia Ricks , Medical Xpress Teplizumab delays type 1 diabetes (T1D) in at-risk individuals in TN10 trial, but participants respond differently to the treatment. Systemic, non-pathogenic antibody responses to gut bacteria can be quantified by anti-commensal antibody (ACAb) assay. Individuals with higher IgG2 responses to specific gut bacteria are more likely to get early...

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DOES GUT BACTERIA CAUSE OSTEOPOROSIS?

POSTED BY ANDREW YAWN-TULANE “This study established that the gut microbiome is important for our bone health and getting a healthy microbiome composition is important,” Hong-Wen Deng says. “Now that we’ve identified a target in B. vulgatus, we want to lower its abundance.” One of the most common forms of gut bacteria may be to blame...

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We Know a Healthy Gut Fights Infection. New Study Reveals How

Gut bacteria are stronger together when it comes to preventing infectious diseases. When a large, diverse community of gut bacteria compete with pathogens for nutrients, the pathogens may not have enough fuel to colonize and invade the body, according to a new study in Science. The more microbes there are, the more different nutrients they’re...

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Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking

Peer-Reviewed Publication UNIVERSITY OF OXFORD Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking The human gut is home to hundreds of different bacterial species collectively known as the gut microbiome. A major health benefit these provide is to protect the gut against invading pathogens (disease-causing microorganisms) that could cause harmful infections. But...

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The Steep Costs of Disrupting Gut-Barrier Harmony

An Interview With Elena Ivanina, DO, MPH Akash Goel, MDDISCLOSURES November 07, 2023 From Ayurveda to the teachings of Hippocrates, medicine’s earliest traditions advanced a belief that the gut was the foundation of all health and disease. It wasn’t until recently, however, that Western medicine has adopted the notion of gut-barrier dysfunction as a pathologic phenomenon critical...