Long-term use of either cannabis or cannabis-based drugs impairs memory say, researchers. The study has implications for both recreational users and people who use the drug to combat epilepsy, multiple sclerosis, and chronic pain LANCASTER UNIVERSITY Long-term use of either cannabis or cannabis-based drugs impairs memory say, researchers. The study has implications for both recreational...
Category: <span>Neuroscience</span>
Post
4 in 5 adolescent girls have a mental health disorder following sexual assault
July 24, 2018, University College London Eighty percent of young women were found to have a mental health disorder and 55 percent had two or more mental health disorders four to five months after sexual assault, according to a study led by UCL and The Havens, London’s specialist sexual assault referral centres (SARCs) hosted by King’s...
Post
New drug target for remyelination in MS is identified
July 17, 2018 by Ellen Goldbaum, University at Buffalo Remyelination, the spontaneous regeneration of the fatty insulator in the brain that keeps neurons communicating, has long been seen as crucial to the next big advance in treating multiple sclerosis (MS). However, a lack of understanding of how remyelination is stymied in the disease has hampered these...
Post
Modulation of anti-tumor immunity by the brain’s reward system
Abstract Regulating immunity is a leading target for cancer therapy. Here, we show that the anti-tumor immune response can be modulated by the brain’s reward system, a key circuitry in emotional processes. Activation of the reward system in tumor-bearing mice (Lewis lung carcinoma (LLC) and B16 melanoma) using chemogenetics (DREADDs), resulted in reduced tumor weight....
Post
Neurodevelopmental Disorders Involving Epilepsy Include Some Distinct De Novo Variants
Jun 25, 2018, | staff reporter NEW YORK (GenomeWeb) – Members of an international team led by investigators at the University of Leipzig Hospitals and Clinics have started characterizing the distinct de novo variants (DNVs) involved in neurodevelopmental disorders (NDDs) that cause epilepsy symptoms. Using the DNV profiles of the members of 6,753 parent-child trios affected by diverse NDDs,...
Post
Rehabilitating the mind could improve outcomes after spinal cord injury
July 16, 2018, Heriot-Watt University A study led by Heriot-Watt University has explored how individuals with spinal cord injuries perceive the space around them. The findings suggest additions are needed to the rehabilitation programmes adopted post-injury to allow the whole person to be treated, not just the physical body. Credit: CC0 Public Domain At present, approximately...
Post
One step closer to finding a cure for brain diseases
July 16, 2018, DGIST (Daegu Gyeongbuk Institute of Science and Technology) A research team led by Professor Jaewon Ko and Ji Won Um from Department of Brain and Cognitive Sciences identified a new principle of formation of brain synapses through synaptic binding protein complexes. Fig 1. Molecular model of PTPσ signaling pathways in heterologous synapse...
Post
‘Concussion pill’ shows promise in pre-clinical pilot study
July 16, 2018, University of Miami Leonard M. Miller School of Medicine In 2016, funded by a $16 million grant from Scythian, the multidisciplinary Miller School team embarked on a five-year study to examine the effects of combining CBD (a cannabinoid derivative of hemp) with an NMDA antagonist (an anesthetic used in animals and humans) for...
Post
Convergence of synaptic signals is mediated by a protein critical for learning and memory
Researchers at the Max Planck Florida Institute for Neuroscience show that protein Kinase C is a novel information integrator, keeping tabs on the recent history of neighboring synapses while simultaneously monitoring local synaptic input MAX PLANCK FLORIDA INSTITUTE FOR NEUROSCIENCE Inside the brain, is a complex symphony of perfectly coordinated signaling. Hundreds of different molecules...
Post
The secret sulfate code that lets the bad Tau in
Research uncovers details of how neurodegeneration-related proteins enter cells AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Vampires can turn humans into vampires, but to enter a human’s house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how cells invite inside corrupted...