September 6, 2024 by Michael David Mitchell, Ecole Polytechnique Federale de Lausanne Gradient of cervical spinal cord functional connectivity along the SMC network. Credit: Imaging Neuroscience (2024). DOI: 10.1162/imag_a_00284The brain and spinal cord are the central pillars of the human central nervous system (CNS), orchestrating everything from movement to sensation. Despite significant advances in neuroscience,...
September 5, 2024 by Chapman University Credit: Unsplash/CC0 Public DomainA new study published in Nature Communications examines how the brain initiates spontaneous actions. In addition to demonstrating how spontaneous action emerges without environmental input, this research has implications for the origins of slow ramping of neural activity before movement onset—a commonly-observed but poorly understood phenomenon....
September 4, 2024 by Michaela Martinez, Duke University A new tool to model peripheral nerve stimulation rapidly discovered optimal electrical waveforms (white traces) which, when delivered through the metal contacts of a cuff electrode placed on the vagus nerve, activates only therapeutic target fibers (in green) to avoid side effects. The optimization process involves testing...
September 3, 2024 by CUNY Advanced Science Research Center Cultured p53 null OPC over-expressing PDGF-BB are highly proliferative and tend to aggregate in low-adhesion conditions. Credit: Neoplasia (2024). DOI: 10.1016/j.neo.2024.101042A new study from researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) sheds light on why certain oligodendrocyte progenitor cells...
September 3, 2024 by Ingrid Fadelli , Medical Xpress (A) Study design. (B) UMAP embedding of nuclei assigned to 11 excitatory, 10 inhibitory, and 3 glial types using DNA methylation in 100 kb bins. (C) RNA expression and gene body DNA methylation at non-CG sites (mCH) for cell type marker genes. (D) Correspondence of mRNA,...
September 2, 2024 by Hillary Smith, University of Kentucky UK researchers find Alzheimer’s-like brain changes in long COVID patientsResearch illustration by Tom Dolan. Credit: University of KentuckyNew research from the University of Kentucky’s Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen...
August 26, 2024 by Tejasri Gururaj , Medical Xpress Neural activity gives information about how fruit flies respond to various sensory stimuli, revealing insights into how they process and encode these experiences into short-term and long-term memories. Credit: Cheng Huang. Fly image credit: https://prints.sciencesource.com/featured/6-fruit-fly-drosophila-melanogaster-oliver-meckes-eye-of-science.html.In a recent study published in Nature, researchers from Stanford University and...
August 30, 2024 by Rajalaxmi Natarajan, Baylor College of Medicine Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01740-1 A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital, reveals that the protein Tau—a key player implicated in several neurodegenerative conditions including Alzheimer’s disease—also...
By Vijay Kumar MalesuReviewed by Susha Cheriyedath, M.Sc. Uncovering the molecular interactions between fibrin and the SARS-CoV-2 spike protein, researchers pave the way for targeted therapies that could curb the devastating effects of long COVID. Fibrin drives thromboinflammation and neuropathology in COVID-19. Image Credit: Juan Gaertner / Shutterstock In a recent study published in the...
August 30, 2024 by Chris Packham , Medical Xpress Examples of axial and sagittal MWF parameter maps averaged across participants with either lower, moderate, or higher VO2max levels. Participants were drawn from the full age range as well as from restricted age ranges to mitigate the effect of age. Results are shown for representative slices....
