Emily Shiffer June 17, 2022 In a surprising discovery that flies in the face of conventional medicine, McGill University researchers report that treating pain with anti-inflammatory medication, like ibuprofen or aspirin, may promote pain in the long term. The paper, published in Science Translational Medicine, suggests that inflammation, a normal part of injury recovery, helps resolve acute pain and...
Category: <span>Pain/Inflammation</span>
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Pain-related gamma-band oscillations reflect pain perception
by Zhang Nannan, Chinese Academy of Sciences Gamma-band oscillations encode pain sensitivity at both within-subject (a) and between-subject levels (b). Credit: Hu Li When you go to the doctor, do you feel that your pain is accurately assessed? The doctor may ask you to describe your pain verbally or to fill in a questionnaire. Traditionally,...
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Possible new way to reduce pain inspired by chickens
by Nina Bai, Stanford University Medical Center Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI163735 Stanford Medicine researchers have discovered a possible new way to treat pain without the use of opioids. By targeting a specific area of a well-known pain receptor, they were able to reduce pain sensitivity in mice without affecting the receptor’s other functions,...
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Largest study on long-term follow-up of chronic pancreatitis patients highlights need for closer monitoring after surgery
AMERICAN COLLEGE OF SURGEONS VIDEO: RESEARCHERS EVALUATED LONG-TERM SURVIVAL RATES AND OUTCOMES FROM 493 PATIENTS WHO UNDERWENT 555 OPERATIONS FOR CHRONIC PANCREATITIS AT THE UNIVERSITY OF CINCINNATI MEDICAL CENTER BETWEEN 2000 AND 2020. THEY FOUND A HIGH (95.5%) 1-YEAR SURVIVAL RATE AMONG PATIENTS BUT A MUCH LOWER (63.5%) 10-YEAR SURVIVAL RATE. PANCREATITIS CAUSED BY ALCOHOL...
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Watch Your Words (To Ease Pain)
The right words from a doctor or nurse can reduce a patient’s pain, promote healing and calmness, and even encourage a patient to take medications properly. The prototype wristwatch here, called CommSense, offers meaningful, real-time ways to improve how doctors and nurses talk with their patients. Illustration by Sanjay Suchak, University of Virginia Communications But clinicians’...
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Fatty acid affects sensitivity of psoriasis plaques to heat, pain
by Tracey Peake, North Carolina State University Linoleic acid (LA) metabolites are found in both the free and total pools of fatty acids in human skin. A box represents the schematic depiction of a) LA or oxylipins (i.e., 9,13-EHL and 9,10,13-THL) derived from LA are esterified into lipid membranes. b) Hydrolysis by enzymes such as...
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Researchers study pain-relieving neural mechanisms by activation of the motor cortex
by Universitätsklinikum Heidelberg Stained nerve tracts in the motor cortex of a mouse. Credit: Heidelberg University Hospital The motor cortex controls the voluntary movement of muscles. It remains largely unclear why its electrical or magnetic stimulation can alleviate therapy-resistant chronic pain—albeit unreliably. An interdisciplinary research group at the Medical Faculty of Heidelberg (MFHD) has now tracked down...
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Radiofrequency ablation for back pain
Radiofrequency ablation (RFA) is a minimally invasive treatment that can sometimes relieve chronic back pain. During the procedure, a doctor inserts a thin metal probe into the painful area. The probe emits radiofrequency energy that creates heat and destroys the nerve tissue that is causing pain. RFA is a relatively new procedure, though researchers have yet to...
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Molecular hydrogen as a new strategy for the treatment of chronic pain
UNIVERSITAT AUTONOMA DE BARCELONA In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances....
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Pain Relievers Like Ibuprofen and Naproxen May Worsen Arthritis Inflammation
By RADIOLOGICAL SOCIETY OF NORTH AMERICA NOVEMBER 21, 2022 According to new research, taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may actually worsen inflammation in the knee joint over time. Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time. This is according to a...