by University of Texas at Dallas A short term HFD regime does not induce the development of obesity nor hyperglycemia. (a) Mice were assigned either a HFD or chow diet at 6 weeks of age for 9 weeks. Weight assessment was performed weekly and blood glucose measurements were performed every weeks starting at week zero....
Samantha Lande November 10, 2022 Jill Krapf’s patients are often too embarrassed to tell her about discomfort in their clitoris. “I ask all of my patients about clitoral pain, and it is often the first time they have ever been asked about this,” says Krapf, MD, the associate director of the Center for Vulvovaginal Disorders, a private...
by Bert Gambini, University at Buffalo Credit: Pixabay/CC0 Public Domain Racial and ethnic disparities in pain prevalence in the U.S. are far larger than previously realized, according to the results of a new study co-written by a University at Buffalo medical sociologist. The current research represents the first portrait of U.S. pain prevalence across six...
By Andrew Joseph Nov. 3, 2022 Reprints PATRICK SISON/AP Federal health officials on Thursday updated their recommendations for using opioids to treat pain, removing specific dose and duration targets that pain experts said had caused unintended harm. The new guidance, released by the Centers for Disease Control and Prevention, reflects the evolution in thinking of how...
by American Society of Anesthesiologists Credit: Unsplash/CC0 Public Domain Wearing special green eyeglasses for several hours a day reduces pain-related anxiety and may help decrease the need for opioids to manage severe pain in fibromyalgia patients and possibly others who experience chronic pain, according to a study being presented at the Anesthesiology 2022 annual meeting....
FRIEDRICH-ALEXANDER-UNIVERSITÄT ERLANGEN-NÜRNBERG New substances that activate adrenalin receptors instead of opioid receptors have a similar pain relieving effect to opiates, but without the negative aspects such as respiratory depression and addiction. This is the result of research carried out by an international team of researchers led by the Chair of Pharmaceutical Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg...
by Indiana University Screenshot of OneSheet, annotated. © 2022 Epic Systems Corporation. Credit: JAMIA Open (2022). DOI: 10.1093/jamiaopen/ooac074 The Chronic Pain OneSheet, a clinical decision support tool developed by the Indiana University Richard M. Fairbanks School of Public Health, is now available for all primary care providers this month at Eskenazi Health. Designed to help primary care providers treat patients with...
by University of California, San Francisco Newly identified α2AAR agonists are analgesic without sedation.More than 301 million molecules were docked against the activated α2BAR. Experimental testing identified α2AAR agonists with diverse chemical scaffolds. The experimental structure of the ‘9087-α2AAR complex superposed closely to the computational prediction. The newly discovered agonists had efficacy in an in...
by Bob Yirka, Medical Xpress The circadian rhythm and melatonin production of a human. Credit: Srruhh, CC BY-SA 4.0 , via Wikimedia Commons A team of researchers with members from Université Claude Bernard Lyon, Hospices Civils de Lyon and Paris-Saclay Université has found a link between pain sensitivity and a person’s circadian rhythm. In their paper...
BY QUINN PHILLIPS | AUGUST 2, 2022 The U.S. Food and Drug Administration (FDA) has approved a neurostimulation device from DyAnsys, Inc., to treat pain related to diabetic peripheral neuropathy, according to a press release from the company. The newly approved device, called First Relief, is what’s known as a PENS (percutaneous electrical neurostimulation) device. That means...
